Preventing cough during bronchoscopic procedures with different drugs
Effects of Adding Intravenous Lidocaine, Alfentanil Before Bronchoscopic Insertion for Preventing Cough During Bronchoscopic Spraying of Local Anesthetics in Non-intubated Bronchoscoopic Interventions
NA · National Taiwan University Hospital · NCT05072236
This study is testing different drugs to see if they can help prevent coughing during bronchoscopic procedures for people who need them.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 20 Years to 65 Years |
| Sex | All |
| Sponsor | National Taiwan University Hospital (other) |
| Locations | 1 site (Taipei) |
| Trial ID | NCT05072236 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of various intravenous drugs, including lidocaine and alfentanil, in preventing cough during bronchoscopic procedures. Coughing can lead to complications such as airway spasm and hemodynamic instability, which can interrupt the procedure. Participants will receive one of the drugs or a placebo (normal saline) one minute before the bronchoscopic insertion, and various physiological responses will be monitored and analyzed. The study aims to improve the safety and efficacy of bronchoscopic interventions by minimizing cough-related complications.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for bronchoscopic interventions for lung tumors requiring intravenous anesthesia.
Not a fit: Patients undergoing conventional bronchoscopy without any interventions will likely not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the safety and effectiveness of bronchoscopic procedures for patients with lung tumors.
How similar studies have performed: Previous studies have explored various methods to prevent cough during bronchoscopic procedures, but this specific approach using these drugs is less commonly tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients planned to receive bronchoscopic interventions for lung tumors with intravenous anesthesia. Exclusion Criteria: * conventional bronchoscopy without interventions such as EBUS, tracheal tumore excision
Where this trial is running
Taipei
- National Taiwan University Cancer Center Hospital — Taipei, Taiwan (RECRUITING)
Study contacts
- Study coordinator: cheng yajung
- Email: chengyj@ntu.edu.tw
- Phone: 0930050762
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Lung Diseases, Total Intravenous Anesthesia, Bronchoscopic Interventions, cough, desaturation, ventilation, bronchoscopic interventions