Preoperative Maxigesic to reduce remifentanil needs during surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial gives adults scheduled for general anesthesia a preoperative dose of Maxigesic (combined IV ibuprofen and acetaminophen) and records intraoperative remifentanil use. Intraoperative nociception and opioid dosing are monitored, with total remifentanil requirement as the main outcome. The Analgesia Nociception Index (ANI), a heart-rate variability–based monitor, is used to track real-time nociception during anesthesia. The study is performed at Ajou University School of Medicine in Suwon among ASA class 1–3 patients aged 19–60.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients (19-60 years old) with ASA physical status 1, 2, 3
* Scheduled surgery under general anesthesia

Exclusion Criteria:

* The patient does not conset
* Pregnancy
* hepatic disorder
* Renal disorder
* Asthma
* Hypersensitivity to the NSAIDs or acetaminophen
* Patients receiving chronic pain therapy
* Drug dependence
* Patients taking psychiatric drugs
* Alcoholics
* History of gastrointestinal ulcer or bleeding

Where it's running

• Ajou university school of medicine
  Suwon, Gyeonggi-do, South Korea Recruiting

Study contacts

• Principal investigator: In Kyong Yi, MD — Ajou University School of Medicine
• Study coordinator: In Kyong Yi, MD
• Email: lyrin01@gmail.com
• Phone: +82-31-219-5579

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.