Preoperative Carbohydrate Drink Before Bariatric Surgery in Metabolic Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized study, adults with metabolic syndrome undergoing bariatric surgery are assigned to either a preoperative carbohydrate drink or a placebo, after a standard fasting protocol. The main outcome is gastrointestinal recovery after surgery, measured by GI-3 criteria, along with time to recovery and other recovery-related measures. Secondary outcomes include nausea, quality of recovery, and length of hospital stay. Safety and other perioperative data will also be collected to assess overall impact. The study is conducted at a single center in Chongqing, China, with 1:1 randomization and blinded placebo control for the beverage.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. adults aged 18-65 years;
2. diagnosis of metabolic syndrome (≥3 of the following: elevated waist circumference, elevated triglycerides, elevated blood pressure, elevated fasting glucose, and reduced HDL-C);
3. eligibility for bariatric surgery(body mass index ≥35 kg/m² or metabolic disease with body mass index 27.5-34.9 kg/m²), with planned Roux-en-Y gastric bypass or sleeve gastrectomy;
4. provision of written informed consent and willingness to complete follow-up.

Exclusion Criteria:

1. gastrointestinal motility disorders;
2. severe cardiovascular, pulmonary, hepatic, or renal dysfunction;
3. HbA1c ≥8.0%;
4. fasting plasma glucose \>10.0 mmol/L at the preoperative assessment;
5. malnutrition;
6. known allergy to carbohydrate preparations;
7. pregnancy or lactation;
8. previous bariatric or gastrointestinal surgery;
9. chronic use of medications known to substantially affect gastrointestinal motility.

Where it's running

• The First Affiliated Hospital of Chongqing Medical University（No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China）
  Chongqing, Chongqing Municipality, China Recruiting

Study contacts

• Study coordinator: Wei Ke, PhD
• Email: wk202448@hospital-cqmu.com
• Phone: +86 13883904332

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.