Prehabilitation and rehabilitation for brain tumor patients
Official title: Joan Ribas Araquistain Program for Research and Therapeutic Innovation in Prehabilitation, Rehabilitation and Comprehensive Approach to the Sequelae of Brain Tumors
Run by Institut Guttmann · NCT05844605 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing a new approach that combines brain stimulation and training to see if it helps adults with brain tumors get ready for surgery and improve their recovery.
Quick facts
| Phase | Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Institut Guttmann Academic / other |
| Locations | 1 site (Badalona, Cataluña) |
| Trial ID | NCT05844605 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults diagnosed with a brain tumor requiring neurosurgery who can participate in at least 10 sessions of the prehabilitation protocol.
✕Probably not a fit
Patients with unstable medical conditions or significant musculoskeletal disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot feasibility trial investigates the Neuromodulation-Induced Cortical Prehabilitation (NICP) approach for adults with brain tumors who are eligible for neurosurgery. Participants will undergo a structured prehabilitation protocol involving non-invasive neuromodulation techniques, such as TMS and tDCS, combined with motor and cognitive training sessions. The study aims to assess the feasibility of the intervention, including adherence, safety, and patient satisfaction, while exploring the neuroplastic mechanisms that may enhance surgical outcomes. Clinical, neuroimaging, and neurophysiology assessments will be conducted throughout the intervention timeline.
Why it matters
Potential benefit: If successful, this approach could improve surgical outcomes and enhance the quality of life for patients with brain tumors.
How similar studies have gone: While few case reports have shown positive results with invasive neuromodulation, this non-invasive approach is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosis of brain tumour requiring neurosurgery * ability to undertake at least 10 sessions of prehabilitation protocol * tumour location posing the patient at risk of developing post-operative neurological deficits, for instance at the level of upper limb motor function and speech production * ability to understand the general purpose of the prehabilitation program and understand simple instructions * being willing to participate and sign the informed consent * being able to sit unassisted for one hour. Exclusion Criteria: * any contraindication for magnetic resonance imaging or transcranial magnetic stimulation * unstable medical conditions * musculoskeletal disorders that may significantly affect functional training * pain, depression, fatigue that may significantly affect functional training * history of alcohol/drug abuse
Where it's running
-
Institut Guttmann
Badalona, Cataluña, Spain Recruiting
Study contacts
- Study coordinator: Jose M Tormos Muñoz, PhD
- Email: jmtormos@guttmann.com
- Phone: 0034686940393
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.