Clinical trial Recruiting at 2 sites Observational Ages 18 and up

Predictors of transmural NOMI in ICU patients with suspected acute mesenteric ischemia

Official title: Mesenteric Ischemia in the ICU: A Prospective Observational Study Across Estonian Regional Hospitals

Run by University of Tartu · NCT07610356 · Data updated 2026-11-12

This study looks at ICU patients with suspected acute mesenteric ischemia to see which factors best predict transmural non-occlusive mesenteric ischemia.

More Acute Mesenteric Ischemia trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment150 (estimated)
SponsorUniversity of Tartu
Academic / other
Locations2 sites (Tallinn, Tallinn and 1 other locations)
StatusRecruiting
StartedJune 6, 2022
Main results expectedJune 5, 2026
Study endsSeptember 5, 2026
Registry record updatedMay 28, 2026
Trial IDNCT07610356 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults in the ICU with clinical suspicion of acute mesenteric ischemia during their stay.

Probably not a fit

Patients without NOMI or AMI suspicion, or those outside the ICU context, are less likely to benefit from the study insights.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, multicenter observational study aims to identify independent predictors of transmural NOMI among ICU patients with suspected acute mesenteric ischemia. Researchers will collect data on demographics, comorbidities, clinical signs, lab results, imaging findings, management, and outcomes across NOMI, other AMI forms, and suspected but unconfirmed cases. The study will describe variation in presentation and care, helping to better stratify risk and guide diagnostics in the ICU setting. No interventional treatments are performed; the study observes natural history and associations. Data will come from two Estonian centers: North Estonia Medical Centre and Tartu University Hospital.

Why it matters

Potential benefit: If successful, the findings could improve early identification and risk stratification for NOMI in ICU patients, potentially guiding faster diagnosis and management.

How similar studies have gone: Prior work on NOMI and AMI has shown the value of identifying predictors, though data specific to ICU-probed NOMI remain limited, making this study's focus relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria

\- Adult ICU patients in whom clinical suspicion of acute mesenteric ischemia is raised during their ICU stay.

Exclusion criteria

* Patients who develop acute mesenteric ischemia outside of the intensive care unit,
* Confirmed strangulating bowel obstruction,
* Individuals younger than 18 years,
* Chronic mesenteric ischemia without an acute event.

Where it's running

  • North Estonia Medical Centre
    Tallinn, Tallinn, Estonia
    Recruiting
  • Tartu University Hospital
    Tartu, Tartu, Estonia
    Recruiting

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.