Identifying biomarkers for acute intestinal ischemia
Official title: Searching Biomarkers of Acute Intestinal Ischemic Injuries
Run by Assistance Publique - Hôpitaux de Paris · NCT03518099 · Data updated 2026-11-12
This study is trying to find new markers in the blood that can help doctors quickly diagnose acute intestinal ischemia in patients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 556 (estimated) |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Clichy) |
| Status | Recruiting |
| Started | November 16, 2018 |
| Main results expected | December 31, 2027 |
| Study ends | July 30, 2028 |
| Registry record updated | December 16, 2025 |
| Trial ID | NCT03518099 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who present with acute abdominal pain and require a CT scan for diagnosis.
✕Probably not a fit
Patients who do not undergo an abdominal CT scan or are under 18 years old may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to identify accurate biomarkers for acute mesenteric ischemia, particularly in its early stages. It involves analyzing biological samples from patients and controls, which will be stored in a biological library for further examination. The analysis will be conducted at several prestigious institutions, including Paris V University and Imperial College London, using both established and novel -omics methods to determine candidate markers. The goal is to improve diagnostic capabilities and treatment strategies for this severe condition.
Why it matters
Potential benefit: If successful, this study could lead to earlier and more accurate diagnosis of acute mesenteric ischemia, potentially reducing mortality rates and improving patient outcomes.
How similar studies have gone: Other studies have shown promise in identifying biomarkers for similar conditions, but this specific approach is innovative and may provide new insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age\> 18 years * Acute abdominal pain requiring an injected abdominal injected CT scan, at best at non-injected / early arterial / portal time * Admitted or attended in Beaujon and / or Bichat hospitals * Patient covered by a social security scheme * Written consent Exclusion Criteria: • lack of abdominal CT scan
Where it's running
-
Corcos Olivier
Clichy, France Recruiting
Study contacts
- Study coordinator: olivier corcos
- Email: olivier.corcos@aphp.fr
- Phone: 140875000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Predictors of transmural NOMI in ICU patients with suspected acute mesenteric ischemia
This study looks at ICU patients with suspected acute mesenteric ischemia to see which factors best predict transmural non-occlusive mesenteric ischemia.
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Life after acute mesenteric ischemia
See how adults treated for acute mesenteric ischemia at Strasbourg University Hospitals between 2010 and 2022 are doing in terms of quality of life.
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Blood markers to help diagnose acute mesenteric ischemia
We will test whether measuring adenosine deaminase in blood helps doctors quickly diagnose acute mesenteric ischemia in adults who come to hospital with severe unexplained abdominal pain.
-
Oral antibiotics for treating acute mesenteric ischemia
This study is testing if giving oral antibiotics to patients with acute mesenteric ischemia can help them survive better and avoid surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.