Predicting lymphedema risk in inflammatory breast cancer patients using preoperative body impedance analysis
Official title: Prediction Of Lymphedema In Patients With Inflammatory BreastCancer Using Preoperative Bioimpedance Measurements
Run by M.D. Anderson Cancer Center · NCT07855627 · Data updated 2026-11-12
This study tests whether a preoperative bioimpedance test can help identify IBC patients who are at risk for developing lymphedema.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 150 (estimated) |
| Sponsor | M.D. Anderson Cancer Center Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Houston, Texas) |
| Status | Recruiting |
| Started | September 16, 2026 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2029 |
| Registry record updated | October 2, 2026 |
| Trial ID | NCT07855627 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 18 or older with newly diagnosed inflammatory breast cancer who have not had prior breast or axillary surgery and are eligible for standard care (neoadjuvant therapy, mastectomy with/without axillary surgery, and radiation).
✕Probably not a fit
Patients who have already undergone breast or axillary surgery or who cannot undergo preoperative bioimpedance measurements may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study explores the use of bioimpedance analysis (BIA) before surgery to describe risk factors for arm lymphedema in women with newly diagnosed inflammatory breast cancer. It aims to reliably describe risk factors for development of breast-cancer–related lymphedema (BCRL) in IBC using BIA. Participants are women aged 18 and older with no prior breast or axillary surgery, undergoing standard treatments such as neoadjuvant therapy, mastectomy with or without axillary surgery, and radiation, with follow-up to monitor lymphedema outcomes. The lead site is UT MD Anderson Cancer Center, with M.D. Anderson as the sponsor, focusing on how preoperative measurements relate to subsequent edema risk.
Why it matters
Potential benefit: If successful, the study could help clinicians identify patients at higher risk for lymphedema and tailor monitoring and prevention strategies accordingly.
How similar studies have gone: Prior research in related cancers has used bioimpedance to monitor lymphedema, showing potential for risk stratification, though application specifically in inflammatory breast cancer is less established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Eligibility Criteria All women≥18 years old with newly diagnosed inflammatory breast cancer without prior breast/axillary surgery who are eligible for standard of care (NST, MRM, and radiation therapy). Exclusion Criteria Prior breast/axillary surgery. Participants with pacemakers or other implanted electronic medical devices. Participants with implanted metallic material. All vulnerable populations, including children, pregnant women, and cognitively impaired adult
Where it's running
-
UT MD Anderson Cancer Center
Houston, Texas, United States Recruiting
Study contacts
- Principal investigator: Anthony Lucci, MD — UT MD Anderson Cancer Center
- Study coordinator: Anthony Lucci, MD
- Email: ALucci@mdanderson.org
- Phone: 713-563-1871
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.