Predicting kidney stone recurrence and complications using precision medicine
Prediction of Recurrence and Complications of Nephrolithiasis Using a Precision Medicine Approach
This study is trying to find out what causes kidney stones to come back so that we can help people avoid getting them again.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 2000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens) |
| Trial ID | NCT05237063 on ClinicalTrials.gov |
What this trial studies
This study aims to identify the clinical, biological, genetic, molecular, and environmental factors that predict the recurrence of kidney stones, a common condition affecting a significant portion of the population. Participants will provide blood and urine samples during routine follow-up visits over a period of five years. The samples will be analyzed to uncover determinants that could help in managing and preventing future episodes of nephrolithiasis. The study is designed to enhance understanding of kidney stone formation and recurrence.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older who have experienced at least one renal colic attack.
Not a fit: Patients who are pregnant, breastfeeding, or unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to personalized prevention strategies for patients at risk of recurrent kidney stones.
How similar studies have performed: While there have been studies on kidney stones, this precision medicine approach focusing on a comprehensive set of predictive factors is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (≥18 years old), male or female , * Persons able to understand and object to the information provided (at the discretion of the investigator) * Patient affiliated to social security * Patient agreeing to sign the informed consent form * patient having presented at least one renal colic attack before inclusion Exclusion Criteria: * Pregnant or breastfeeding woman. * Persons deprived of liberty, * Adults under legal protection guardianship, or curators or unable to express their consent. * Patient refusing to participate in the study * Patient in an emergency situation
Where this trial is running
Amiens
- CHU Amiens Nord — Amiens, France (Recruiting)
Study contacts
- Study coordinator: Dominique Eladari, Pr
- Email: dominique.eladari@inserm.fr
- Phone: 06 13 03 99 01
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.