Predicting difficult intubation from voice patterns before surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-center, observational study enrolling up to 300 patients aged 15–70 who are scheduled for elective general anesthesia with tracheal intubation. Researchers will analyze voice recordings of selected vowels to identify patterns associated with difficult airway anatomy, using machine learning, while standard care and anesthesia procedures remain unchanged. The goal is to create a quick, non-invasive preoperative risk tool to help anesthesiologists anticipate challenging intubations and improve patient safety. The study excludes individuals with speech, hearing, or craniofacial conditions that could confound voice measurements or airway assessment. No interventions are being tested; data collection is observational and non-interventional.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients scheduled for elective general anesthesia with tracheal intubation.

Exclusion Criteria:

* Patients with speech and pronunciation disorders (vocal cord diseases, cleft palate, craniofacial deformities, extensive tooth defects, cleft lip).
* Hearing impairment (difficulty in communication, inaccurate repetition).
* Patients with central nervous system diseases causing significant pronunciation abnormalities.
* Patients contraindicated for direct laryngoscopy (e.g., post-chemotherapy in the pharynx, diseases prone to mucosal bleeding, etc.) that affect group allocation, as well as those unable to complete the recording or temporarily reassigned to other anesthesia methods.

Where it's running

• Shanghai Sixth People's Hospital Affiliated with Shanghai Jiao Tong University School of Medicine
  Shanghai, China Recruiting

Study contacts

• Study coordinator: Jun Yao
• Email: guoxinger@126.com
• Phone: +86 18930173671

Similar studies

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.