Predicting and understanding pain six months after radiotherapy for head and neck cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a two-center prospective cohort of about 120 French-speaking patients with a first head and neck cancer treated with radiotherapy who will be followed to six months after treatment. Participants will complete standardized questionnaires about pain, analgesic use, substance use (tobacco and alcohol), mood symptoms, fatigue, and global quality of life. Investigators will measure the prevalence of chronic pain at six months and analyze correlations between persistent pain and continued addictions, depressive symptoms, asthenia, and quality-of-life scores. The goal is to identify clinical patterns that predict which patients are at higher risk of long-term pain and related psychosocial problems.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with a first Head and neck cancer whose therapeutic sequence involves radiotherapy
* Patient over 18 years of age
* Having given written consent
* patient not previously treated with radiotherapy
* Life expectancy \> 3 months
* World Health Organization (WHO) score \< 3
* Histologically proven Head and Neck cancer
* Stable patient, with no signs of recurrence or other progressive neoplasia at the time of the examination
* Patient treated with radiotherapy
* Patient fluent in French

Exclusion Criteria:

* Non-consenting patient
* History of malignancy, other than treated and cured basal cell or cervical cancer
* Patient who has had a salvage surgery other than lymph node removal
* Patient with evidence of recurrence or other progressive neoplasia at the time of examination
* Patient who has had previous mutilating surgery (causing sequelae of swallowing and eating)
* Uncontrolled infectious pathology
* Patient under 18 years of age
* Patient who is not fluent in French
* Patient with a psychiatric pathology that could disrupt the study or prevent the interpretation of the results.

Where it's running

• Caen University Hospital
  Caen, France Recruiting

Study contacts

• Principal investigator: maxime humbert, MD — University Hospital, Caen
• Study coordinator: Maxime Humbert, MD
• Email: humbert-m@chu-caen.fr
• Phone: 0231064640

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.