Precision navigation to boost cancer screening participation in high-risk communities

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this cluster-randomized trial, communities are assigned to a precision navigation program, usual health education, or a waiting control. Participants are high-risk adults from urban screening programs and are not yet screened for their high-risk cancer type. The study uses two cohorts based on the number of cancer types they are at risk for, and compares completion of recommended screenings across groups. It is conducted at multiple sites in Hunan Province, led by Hunan Cancer Hospital.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Aged 45 to 74 years.
2. Permanent resident of a participating community, defined as having lived in the community for at least 6 months during the past 12 months.
3. Participating in the urban cancer screening program.
4. Identified by the program risk assessment questionnaire as being at high risk for at least one of the following cancers: lung cancer, breast cancer, colorectal cancer, upper gastrointestinal cancer, or liver cancer.
5. Has not yet completed the corresponding free clinical screening test for the high-risk cancer type or types.
6. Able to complete electronic questionnaires and read intervention materials independently or with assistance. Paper materials and staff explanation will be provided for participants who do not use smartphones.
7. Able and willing to provide written informed consent.

Exclusion Criteria:

1. Previously diagnosed with any of the target cancers, including lung cancer, breast cancer, colorectal cancer, upper gastrointestinal cancer, or liver cancer.
2. Severe cognitive impairment, severe mental illness, or other conditions that prevent the participant from receiving the intervention or completing study questionnaires.
3. Planning to be away from the community for a long period during the next 6 months, defined as cumulative absence of more than 3 months.
4. Currently participating in another interventional study that may affect cancer screening behavior.

Where it's running

• Huaihua Central Hospital (Huaihua Cancer Hospital)
  Huaihua, Hunan, China Recruiting
• Shaoyang Hospital of Traditional Chinese Medicine
  Shaoyang, Hunan, China Recruiting
• Yongzhou Central Hospital
  Yongzhou, Hunan, China Recruiting

Study contacts

• Study coordinator: Haifan Xiao
• Email: xiaohaifan@hnca.org.cn
• Phone: 8615580869827

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.