Platelet-rich plasma injections for joint and tendon problems
Official title: Platelet Rich Plasma for Musculoskeletal Conditions
Run by University of Utah · NCT07231471 · Data updated 2026-11-12
This project will test whether platelet-rich plasma (PRP) injections help people with osteoarthritis and other musculoskeletal conditions reduce pain and improve function over one year.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | University of Utah Academic / other |
| Locations | 1 site (Salt Lake City, Utah) |
| Status | Recruiting |
| Started | December 29, 2025 |
| Main results expected | January 1, 2035 |
| Study ends | January 1, 2035 |
| Registry record updated | May 6, 2026 |
| Trial ID | NCT07231471 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with musculoskeletal pathology that may benefit from a PRP injection who have failed other conservative treatments are ideal candidates, provided they have no active infection, malignancy, platelet disorder, or need for dialysis.
✕Probably not a fit
Patients with active infection at the injection site, active malignancy, known platelet disorders, those on dialysis, or people with conditions unlikely to respond such as very advanced joint destruction may not receive benefit from PRP in this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Participants who receive PRP injections for a variety of musculoskeletal conditions will be enrolled in a registry and followed for 12 months. Standardized outcomes for pain, physical function, and overall patient satisfaction will be collected at scheduled intervals. The registry includes patients treated for knee, hip, shoulder, ankle, elbow, sacroiliac joint issues and common tendinopathies. Data on injection preparation, safety events, and prior conservative treatments will also be recorded to help characterize real-world effectiveness.
Why it matters
Potential benefit: If successful, this work could help demonstrate that PRP offers meaningful pain relief and functional improvement with lower risk than repeat corticosteroid injections, guiding treatment choices for people with MSK conditions.
How similar studies have gone: Previous randomized trials and systematic reviews, especially in knee osteoarthritis and several tendinopathies, have shown PRP to be equal or superior to corticosteroids and hyaluronic acid for pain and function.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18+ years old * Musculoskeletal pathology that may benefit from a PRP injection * Failed other conservative treatments Exclusion Criteria: * No active malignancy * No active infection in the area of injection * No platelet disorder * No active systemic infections * No patients currently undergoing dialysis
Where it's running
-
University of Utah Orthoaedic Center
Salt Lake City, Utah, United States Recruiting
Study contacts
- Study coordinator: Christina Geisler, MS
- Email: christina.geisler@utah.edu
- Phone: 18012133379
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.