Plant-based, online weight loss program with education and support

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study provides a 12-week online plant-based nutrition education program delivered in a community setting. Participants attend weekly physician- and dietitian-led sessions to learn and implement a vegan-style diet and receive practical support. Assessments include body composition via DXA, HbA1c, lipid panel, and a cost analysis at baseline and after 12 weeks. The study will evaluate feasibility, implementation, and efficacy of the program in real-world conditions. Enrollment targets adults with BMI ≥25 (or ≥23 for Asian origin) who have internet access and can attend required measurements in DC and nearby facilities.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* U.S. men and women meeting the age of majority, defined as follows:

Age 19 or older in Nebraska and Alabama. Age 21 or older in Puerto Rico. Age 18 or older in all other states.

* Able and willing to travel to Washington DC for a dual-energy х-rау absorptiometry (DXA) scans before and after the program.
* Able and willing to complete laboratory assessments at a local LabCorp facility before and after the program.
* Able and willing to participate in all components of the study.
* BMI of 25 or more (23 or more in persons of Asian origin).
* Access to the internet.
* English fluency.

Exclusion Criteria:

* Use of recreational drugs in the past 6 months.
* Pregnancy or intention to become pregnant during the study period, as verified by self-report.
* Unstable medical or psychiatric illness.
* Inability to maintain medication regimen as prescribed by personal healthcare provider.
* Current or expected use of any weight loss medication during the study period, including but not limited to, glucagon-like peptide-1 (GLP-1) receptor agonists and combination GLP-1 receptor/glucose-dependent insulinotropic polypeptide (GIP) agonists.
* Use of any weight loss medication within the 12 months preceding the study period, including but not limited to, glucagon-like peptide-1 (GLP-1) receptor agonists and combination GLP-1 receptor/glucose-dependent insulinotropic polypeptide (GIP) agonists.
* Body weight greater than 182 kg.
* Current diagnosis of eating disorder.
* Intention to follow another weight loss method during the study period.

Where it's running

• Physicians Committee for Responsible Medicine
  Washington D.C., District of Columbia, United States Recruiting

Study contacts

• Study coordinator: Vanita Rahman, MD, DipACLM
• Email: vrahman@pcrm.org
• Phone: 202-527-7500

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.