Pilocarpine after cataract and Kahook goniotomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center Phase 3 interventional study enrolls patients having combined cataract surgery with Kahook Dual Blade goniotomy to see if adding postoperative pilocarpine improves surgical success. Participants receive standard postoperative care including topical steroid and antibiotic with pilocarpine added for the intervention group, and outcomes such as intraocular pressure and medication burden are tracked over follow-up. The Kahook procedure removes strips of trabecular meshwork to improve aqueous outflow, while pilocarpine acts by tightening the ciliary muscle and opening trabecular spaces. The trial is conducted at Montefiore with a single provider to standardize surgical technique and postoperative management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with ocular hypertension or open angle glaucoma undergoing combined cataract surgery with KDB in a single surgical center at Montefiore Medical Center with a single provider

Exclusion Criteria:

* Patients with previous history of eye surgeries (including laser procedures)

Where it's running

• Montefiore Wakefield Campus
  The Bronx, New York, United States Recruiting
• Montefiore Medical Center
  The Bronx, New York, United States Recruiting

Study contacts

• Principal investigator: Wen-Jeng (Melissa) Yao, MD — Montefiore Medical Center
• Study coordinator: Wen-Jeng (Melissa) Yao, MD
• Email: WYAO@montefiore.org
• Phone: 718-920-2020

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.