Pharmacist-led opioid stewardship for adults with chronic non-cancer pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, non-randomized interventional program introduces a pharmacist-led Opioid Stewardship Program (OSP) for outpatient adults with chronic non-cancer pain at Korea University Guro Hospital. The OSP includes pharmacist review of opioid prescriptions, patient education, and tailored recommendations communicated to prescribing clinicians. Outcomes from the implementation period will be compared with a historical control to measure changes in the incidence of high-risk opioid prescribing and in patients' awareness, knowledge, and attitudes about opioid use. Eligible participants are adults aged 19–79 who received specified opioid prescriptions in the designated departments during the study window.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Outpatients at the Department of Anesthesiology and Pain Medicine or the Department of Physical Medicine \& Rehabilitation of the study site who received a prescription for opioid analgesics (oral, transdermal, sublingual, or buccal formulations containing oxycodone, fentanyl, tapentadol, hydrocodone, or morphine) due to chronic non-cancer pain during the study evaluation period (from IRB approval date to September 30, 2025)
* Adults aged ≥19 years and \<80 years
* Patients who voluntarily signed a written informed consent form after receiving a full explanation of the study and understanding its purpose

Exclusion Criteria:

* Patients with active cancer
* Patients diagnosed with sickle cell disease
* Patients diagnosed with a life-limiting illness eligible for hospice or palliative care as defined in Article 2 of the 'ACT ON HOSPICE AND PALLIATIVE CARE AND DECISIONS ON LIFE-SUSTAINING TREATMENT FOR PATIENTS AT THE END OF LIFE'
* Pregnant patients
* Patients who were prescribed opioid analgesics within the past month for postoperative pain management
* Patients who were prescribed opioid analgesics within the past month for newly developed pain
* Patients with communication difficulties
* Patients who were prescribed buprenorphine for the treatment of opioid use disorder
* Patients who are deemed inappropriate for study participation at the discretion of the investigator

Where it's running

• Korea University Guro Hospital
  Seoul, Seoul, South Korea Recruiting

Study contacts

• Principal investigator: So Hyun Lee, MS — Korea University Guro Hospital
• Study coordinator: So Hyun Lee, MS
• Email: pharm23@kumc.or.kr
• Phone: +82-2-2626-1611

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.