Personalized web-based intervention for adolescent behavioral health and substance use

Adolescent Screening and Personalized Intervention Resource for Mild/Moderate Substance Use and Co-Occurring Problems

NA · Oregon Research Institute · NCT06306287

This study is testing a personalized online program to see if it helps teenagers with mild to moderate substance use and mental health issues feel better compared to a standard online program.

Quick facts

PhaseNA
Study typeInterventional
Enrollment120 (estimated)
Ages12 Years and up
SexAll
SponsorOregon Research Institute (other)
Locations1 site (Albuquerque, New Mexico)
Trial IDNCT06306287 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of a personalized web-based intervention, eHealth Personalized Approach for Change Efficacy (ePACE), compared to a fixed intervention, eHealth Fixed Approach for Change Efficacy (eFACE), for adolescents experiencing mild to moderate substance use and mental health issues. The intervention is designed to engage youth by allowing them to make choices about the content and level of engagement in their treatment. It incorporates a multi-problem screener and various behavior change and counseling modules that address substance use, interpersonal relations, negative emotions, and stress. The goal is to provide a scalable, accessible resource that can be utilized in various settings, particularly where traditional treatment options are limited.

Who should consider this trial

Good fit: Ideal candidates for this study are adolescents aged 12-17 who live at home, report mild to moderate substance use, and have mental health concerns.

Not a fit: Patients who may not benefit from this study include those with severe mental health issues requiring higher levels of care or those with a sibling already participating in the study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve access to effective early treatment for adolescents struggling with substance use and mental health issues.

How similar studies have performed: Other studies have shown promise in using technology-based interventions for behavioral health, suggesting that this approach could be effective, though the specific combination of personalized and fixed interventions is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Adolescent Inclusion Criteria:

* 12-17 years
* live at home with at least one parent or parent figure
* reporting mild/moderate substance use
* reporting mental health issues
* sufficient English language skills for assessments and intervention

Adolescent Exclusion Criteria:

* a sibling has already participated in the study
* evidence of psychotic or organic state
* high problem severity indicating possible need for higher level of care

Parent Inclusion Criteria:

• sufficient English language skills for assessments and intervention

Parent Exclusion Criteria:

• another parent or parent figure is already participating in the study

Where this trial is running

Albuquerque, New Mexico

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Substance Use, Mental Health Issue

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.