Personalized treatment for smoking cessation in primary care

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates a precision treatment intervention for smoking cessation, comparing its effectiveness to usual care in primary care settings. It utilizes personalized recommendations based on patients' clinical, genetic, and biomarker information to enhance treatment adherence and clinician prescribing practices. The study involves a 2-arm cluster randomized controlled trial with 50 clinicians and 800 eligible patients, aiming to assess the impact of precision treatment on smoking cessation success. The goal is to address gaps in both clinician and patient engagement with tobacco treatment.

Why it matters

Who can join: the full rules

Eligibility Criteria for Primary and Specialty Care Clinicians

* Clinician from participating clinic
* At least 18 years of age
* Can speak and understand English

Eligibility Criteria for Primary Care and Specialty Patients

Inclusion:

* Patient at participating clinic
* Age 18 years or older, inclusive
* Current smoking (cigarettes per day \>=5)
* Can speak and understand English
* Willing to consider medication to help reduce craving or smoking such as nicotine patch, lozenge, or varenicline

Exclusion:

* Active use of smoking cessation medication (within the past 30 days)
* Receipt of smoking cessation medication or prescription for smoking cessation medication (within the past 30 days)
* Having a contraindication for cNRT or varenicline (allergic reactions, current cardiac problems, pregnancy)

Where it's running

• Washington University School of Medicine
  St Louis, Missouri, United States Recruiting

Study contacts

• Principal investigator: Li-Shiun Chen, ScD, MD, MPH — Washington University School of Medicine
• Study coordinator: Li-Shiun Chen, ScD, MD, MPH
• Email: li-shiun@wustl.edu
• Phone: 314-362-3932

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.