Personalized intervention to reduce mortality risks related to alcohol use and cardiovascular health
Can a Radical Transformation of Preventive Care Reduce Mortality by 20% in Low Socioeconomic (SES) Populations? Preparatory Work Focusing on Alcohol Use Disorder (AUD)/Heavy Alcohol Use, HIV Risk, and Cardiovascular Risk
This study tests if a personalized program can help people at risk of heart problems and alcohol-related issues live longer and healthier lives by connecting them to the right healthcare services.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 35 Years to 64 Years |
| Sex | All |
| Sponsor | NYU Langone Health Academic / other |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT05828849 on ClinicalTrials.gov |
What this trial studies
This research investigates whether a personalized intervention can help individuals reduce their risk of dying from preventable causes such as heart attacks, strokes, and substance abuse. The intervention includes navigation to healthcare services, personalized health benefits, and compensation for health-related costs. Participants will be engaged in outreach efforts to ensure they complete necessary health encounters. The study targets individuals with specific risk factors, aiming to improve their overall health outcomes.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 35 to 64 with low socioeconomic status and a high expected mortality risk due to cardiovascular factors or heavy alcohol consumption.
Not a fit: Patients who are already receiving regular care outside the designated health system or have high mortality conditions not included in the study may not benefit.
Why it matters
Potential benefit: If successful, this intervention could significantly lower mortality rates among individuals at high risk due to alcohol use and cardiovascular issues.
How similar studies have performed: While similar interventions have shown promise in addressing health disparities, this specific approach is novel in its combination of navigation, personalization, and compensation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 35 to 64 2. Low SES (≤ $38,000 annual income, based on 2019 20th percentile NYC income, adjusted for family size) 3. Expected mortality ≥1% per year (based on age, sex, race/ethnicity), with ≥1 of the following contributors: 1. 10-year cardiovascular risk ≥10% (assessed by ASCVD risk tool) 2. Heavy alcohol consumption (defined using SAMHSA binge drinking definition, drinking \>4 standard drinks for men and \>3 standard drinks for women on same occasion in past month) 4. Willing to be navigated to Health and Hospitals Corporation of New York health system. 5. Ability to provide written informed consent in English or Spanish Exclusion Criteria: 1. Receives regular care elsewhere than Health and Hospitals Corporation of New York 2. Already diagnosed with high mortality-condition(s) that are not included in the simulation model.
Where this trial is running
New York, New York
- NYC H+H/Bellevue — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: Ronald S Braithwaite, Braithwaite — NYU Langone Health
- Study coordinator: Ronald S Braithwaite, MD
- Email: Scott.Braithwaite@nyulangone.org
- Phone: 212-263-4964
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.