Personalised VT substrate mapping with dynamic voltage mapping during ablation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional trial tests a technique called dynamic voltage mapping in patients undergoing VT ablation to tailor the procedure to individual heart scar patterns. Participants are adults with ischemic or non-ischemic cardiomyopathy who require ablation and have an ICD in place. The approach compares dynamic voltage mapping plus standard ablation to the standard ablation strategy alone, focusing on the accuracy of identifying problematic circuits and the success of VT suppression. The study monitors safety and procedural outcomes in a real-world clinical setting at a single center. No phase designation is provided for this trial.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Scheduled for clinically indicated VT ablation (due to sustained VT episodes or ICD therapies).
* Willing and able to give informed consent for participation in the trial
* Male or female aged between 18-85
* Ischaemic and non-ischaemic cardiomyopathy
* ICD insitu

Exclusion Criteria:

* Unable or unwilling to consent
* NYHA Class IV (end stage heart failure)
* Metastatic cancer
* End stage renal disease
* Pregnant or breast feeding
* Severe frailty

Where it's running

• Liverpool Heart and Chest Hospital NHS Foundation Trust
  Liverpool, United Kingdom Recruiting

Similar studies

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.