Peer recovery coaching to help people with opioid use disorder quit smoking
Official title: Peer Recovery Coaching for Promoting Tobacco Abstinence in People With Opioid Use Disorder
Run by Massachusetts General Hospital · NCT06965153 · Data updated 2026-11-12
This test pairs people on medication-assisted treatment for opioid use disorder with peer coaches to help them quit or reduce smoking.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Massachusetts General Hospital Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | January 1, 2028 |
| Study ends | January 1, 2028 |
| Registry record updated | October 7, 2026 |
| Trial ID | NCT06965153 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older who smoke at least 5 cigarettes per day and are on stable MOUD at MGH, and who want to quit or reduce smoking in the next 3 months.
✕Probably not a fit
Individuals not motivated to quit or reduce smoking, or those with unstable medical or psychiatric conditions that preclude participation, may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial aims to see if adding peer recovery coaching to dual nicotine replacement therapy improves tobacco abstinence or reduction in adults with opioid use disorder who smoke. Participants must be on stable MOUD at Massachusetts General Hospital and want to quit or cut down smoking. The approach leverages the influence of peers with lived OUD experience to support quit attempts and engagement with treatment. The intervention components include Dual NRT and PeerTTS, delivered in a setting accessible to current MOUD patients. Outcomes will inform whether this strategy can augment smoking cessation efforts in MOUD populations.
Why it matters
Potential benefit: If successful, participants may achieve higher quit rates and better overall health by reducing tobacco use while maintaining MOUD.
How similar studies have gone: Previous evidence suggests peer coaching can improve treatment engagement in OUD, but applying it to tobacco cessation in MOUD populations is an emerging area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (≥ 18 years of age) * reporting current daily cigarette smoking (≥ 5 cigarettes per day in past 7 days), * who are interested in quitting or cutting down on smoking in the next 3 months (yes/no), * stable on their medication treatment for OUD (MOUD) at MGH (confirmed with patient's buprenorphine prescriber). Exclusion Criteria: * life expectancies \< 1 year (per chart review by physician Co-I) or with any serious psychiatric or cognitive problem that would preclude ability to provide informed consent (i.e., unstable or untreated bipolar disorder, schizophrenia spectrum disorder, psychotic disorder, or actively suicidal) * participants who have recent unstable cardiovascular or cerebrovascular disease (e.g., recovery phase of acute myocardial infarction, severe cardiac arrhythmias, and cerebrovascular accident; See Human Subjects) per discussion with their MOUD prescriber.
Where it's running
-
Massachusetts General Hospital
Boston, Massachusetts, United States Recruiting
Study contacts
- Principal investigator: Joanna M Streck, PhD — Massachusetts General Hospital
- Study coordinator: Joanna M Streck, PhD
- Email: jstreck@mgh.harvard.edu
- Phone: 617-643-9977
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.