Pain types in people with multiple sclerosis and chronic pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a cross-sectional observational study enrolling adults with MS and chronic pain to classify their pain into nociceptive, neuropathic, nociplastic, or mixed phenotypes using clinical data and quantitative sensory testing. Assessments include pain characteristics, distribution, intensity, fatigue, quality of life, and MS severity, conducted in standardized conditions and focused on the most painful site. Researchers will compare characteristics across pain phenotype groups to understand associations and potential targets for management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Definite diagnosis of multiple sclerosis according to the McDonald criteria
* No MS relapse or high-dose steroid treatment within the previous 3 months
* Pain intensity ≥2 on the Numeric Rating Scale in at least one body region for at least 3 months
* Ability to read, understand, and communicate in Turkish

Exclusion Criteria:

* Pregnancy
* Severe psychiatric disorder and/or severe cognitive impairment confirmed by a neurologist or neuropsychiatrist
* Presence of a serious pathology or disease that may compromise the assessment process or affect clinical decision-making, including metastasis, cancer, untreated or unhealed fractures, neurological disorders other than multiple sclerosis, or a history of diabetes

Where it's running

• Kutahya Health Sciences University Physical Medicine and Rehabilitation Department
  Kütahya, Turkiye, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Nisa TURUTGEN, Msc.
• Email: nisa.turutgen@ksbu.edu.tr
• Phone: 00902742651300

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.