Pain Resilience Program to Increase Physical Activity in Teens
Official title: Physical Activity Pain Resilience
Run by Nationwide Children's Hospital · NCT07049029 · Data updated 2026-11-12
This program will test whether a four-week virtual Pain Resilience Promotion for Youth (PREP-Y) course can help teens ages 12–17 with chronic musculoskeletal pain become more physically active and cope better with their pain.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 12 Years to 17 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Nationwide Children's Hospital Academic / other |
| Locations | 1 site (Columbus, Ohio) |
| Status | Recruiting |
| Started | September 29, 2025 |
| Main results expected | October 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | October 3, 2025 |
| Trial ID | NCT07049029 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are English-speaking adolescents aged 12–17 with a primary chronic musculoskeletal pain disorder lasting more than three months, identified by a pediatric rheumatologist or pain physician.
✕Probably not a fit
Patients whose pain is secondary to another disease (such as sickle cell disease or inflammatory rheumatic disease), those with untreated major psychiatric disorders, or those with developmental delay are excluded and unlikely to benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
PREP-Y is a four-week virtual intervention that teaches resilience skills such as motivation, confidence building, and pain coping to adolescents with chronic musculoskeletal pain. Participants complete surveys and physical activity tests before and after the program and wear activity monitors to track daily movement. The trial is interventional and focuses on feasibility, acceptability, and preliminary changes in activity and pain-related function. Findings will inform refinement of the program and planning for a larger follow-up trial.
Why it matters
Potential benefit: If successful, PREP-Y could help teens increase daily activity and reduce pain-related disability by teaching practical motivation and coping skills.
How similar studies have gone: Behavioral and physical-activity interventions, including cognitive-behavioral approaches, have shown benefits for pediatric chronic pain, but PREP-Y's brief virtual resilience-focused format is relatively new and less studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Between the ages of 12 and 17 * History of chronic musculoskeletal pain for more than 3 months assessed by a pediatric rheumatologist or pain physician * Diagnosis of a primary pain disorder (e.g., juvenile fibromyalgia and other widespread pain conditions, lower back pain, complex regional pain and amplified pain syndrome) * Speaks English as primary language Exclusion Criteria: * Chronic pain secondary to disease (e.g., sickle cell disease or rheumatic disease such as juvenile arthritis, systemic lupus erythematosus) * Presence of an untreated major psychiatric diagnosis (e.g., major depression, bi-polar disorder, psychoses) * History or diagnosis of developmental delay.
Where it's running
-
Nationwide Children's Hospital
Columbus, Ohio, United States Recruiting
Study contacts
- Principal investigator: William Black, PhD — Nationwide Children's Hospital
- Study coordinator: William Black, PhD
- Email: william.black@nationwidechildrens.org
- Phone: 614-472-0717
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.