Pain relief technique for patients undergoing minimally invasive esophagectomy

Clinical Study of Rhomboid Intercostal and Subserratum Plane Block for Postoperative Analgesia in Minimally Invasive Esophagectomy

NA · Fuling Central Hospital of Chongqing City · NCT06092944

This study is testing a new pain relief method for patients recovering from minimally invasive esophagus surgery to see if it helps reduce their pain safely.

Quick facts

PhaseNA
Study typeInterventional
Enrollment96 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorFuling Central Hospital of Chongqing City (other)
Locations1 site (Chongqing)
Trial IDNCT06092944 on ClinicalTrials.gov

What this trial studies

This study investigates the safety and effectiveness of the rhomboid intercostal and subserratum plane (RISS) block for providing postoperative analgesia in patients who have undergone minimally invasive McKeown esophagectomy. The RISS block involves injecting local anesthetics into specific muscle planes to block intercostal nerves, aiming to alleviate pain in the chest and upper abdomen. The study will utilize catheterization for continuous local anesthetic delivery to assess the efficacy and safety of this technique in the context of esophageal cancer surgery.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-75 who have undergone minimally invasive McKeown esophagectomy and meet specific health criteria.

Not a fit: Patients with severe comorbidities, chronic pain conditions, or those who cannot cooperate with assessments may not benefit from this study.

Why it matters

Potential benefit: If successful, this technique could significantly improve pain management for patients recovering from esophageal cancer surgery.

How similar studies have performed: While the RISS block has shown promise in other contexts, its specific application in minimally invasive esophagectomy is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients received MIE-McKeown surgery and were confirmed by postoperative pathology; Age 18-75 years old
* body mass index (BMI) : 18.5\~23.9kg/m2;
* American Society of Anesthesiologists (ASA) grade: Ⅰ\~Ⅱ;
* Clear consciousness, no cognitive impairment;
* Patients informed to participate in the study and signed informed consent.

Exclusion Criteria:

* Infection of the puncture site, abnormal platelet or coagulation function;
* Patients with drug allergy involved in this study;
* Long-term use of analgesic, sedative drugs or a history of heavy drinking;
* Patients with chronic painful diseases;
* With severe heart, liver, kidney and lung dysfunction;
* Infectious diseases, blood, immune, circulatory system diseases; -Communication barriers, can not cooperate with the scale assessment; -
* Other situations not suitable for this study.

Where this trial is running

Chongqing

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Esophagus Cancer, Rhomboid intercostal and subserratum plane block, Ultrasound-guided, Postoperative analgesia, Minimally invasive esophagectomy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.