Clinical trial Recruiting at 1 site Interventional Ages 19 to 44

Pain Neuroscience Education with Sensory Discrimination Training for Chronic Low Back Pain

Official title: Effects of Pain Neuroscience Education With Sensory Discrimination Training on Pain Catastrophizing, Kinesiophobia and Functional Movements Among Patients With Chronic Low Back Pain: A Randomized Controlled Trial

Run by Lahore University of Biological and Applied Sciences · NCT07284407 · Data updated 2026-11-12

A randomized study tests whether adding Sensory Discrimination Training to Pain Neuroscience Education and core exercises helps people with chronic low back pain more than Pain Neuroscience Education and core exercises alone.

More Low Back Pain trials

Quick facts

Study typeInterventional
Ages19 Years to 44 Years
SexAll
Enrollment80 (estimated)
SponsorLahore University of Biological and Applied Sciences
Academic / other
Locations1 site (Lahore)
StatusRecruiting
StartedFebruary 15, 2025
Main results expectedMay 20, 2026
Study endsOctober 15, 2026
Registry record updatedOctober 6, 2026
Trial IDNCT07284407 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 19–44 with mechanical chronic low back pain lasting more than 6 months but less than 2 years and a pain rating above 4/10.

Probably not a fit

Patients with radicular pain, recent surgery, pregnancy, malignancy, neurological deficits, or non-mechanical pain are less likely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This double-blind, parallel-group randomized trial will enroll 80 adults with chronic mechanical low back pain. Participants will be assigned to either Pain Neuroscience Education plus Sensory Discrimination Training and core stability exercises, or Pain Neuroscience Education plus core stability exercises alone, delivered twice weekly for eight weeks. Primary outcome is pain catastrophizing; secondary outcomes include kinesiophobia and functional movements, assessed at baseline, 4 weeks, and 8 weeks. The study is conducted at sites in Lahore, Pakistan, with randomization and blinding designed to minimize bias. The goal is to determine if adding Sensory Discrimination Training provides additional benefits beyond neuroscience education and exercise.

Why it matters

Potential benefit: If successful, the approach could further reduce maladaptive pain beliefs and improve movement, potentially easing disability from chronic low back pain.

How similar studies have gone: Previous work suggests Pain Neuroscience Education can help with pain beliefs, with added sensory training potentially offering incremental gains; this specific combination is being tested for its additive effect.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age: 19 to 44 Both Genders Mechanical low back pain (duration more than 6 months and less than 2 years) \>4/10 Numerical Pain Rating Scale (NPRS)

Exclusion Criteria:

* Pregnancy or post-partum Trauma Psychological Pain Radicular Pain Cancer, tumor, malignancy Neurological Deficit Recent Surgery \<1year

Where it's running

  • 1. Boston Physical Therapy Centre Lahore. 2. Nutricao Clinic Lahore. 3. Model Town Hospital Lahore
    Lahore, Pakistan
    Recruiting

Study contacts

  • Principal investigator: Muhammad Tariq Rafiq — Lahore University of Biological & Applied Sciences
  • Study coordinator: Muhammad Saad Janjua
  • Email: ubs24lmspt023@ubas.edu.pk
  • Phone: +923167995435

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.