Pain neuroscience education program for adults with cancer pain

The Effectiveness of a Pain Neuroscience Education Program Compared to Conventional Treatment on Pain, Biopsychosocial Variables, and Functional Capacity in Adults With Cancer Pain

Not applicable Interventional Instituto Neurociencia Del Dolor · NCT05581784

This study is testing a pain education program to see if it can help adults with cancer pain manage their discomfort better than standard pain treatments.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages40 Years to 75 Years
SexAll
SponsorInstituto Neurociencia Del Dolor Academic / other
Locations4 sites (Iquique and 3 other locations)
Trial IDNCT05581784 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of a pain neuroscience education (PNE) program for adults experiencing cancer-related pain. It involves a randomized controlled design where 80 participants will be divided into two groups: one receiving PNE over 10 weeks and the other receiving conventional pain management. The PNE group will attend 9 educational sessions aimed at enhancing their understanding of pain, complemented by personalized materials. The study will assess outcomes at baseline and after the intervention period to determine the impact on pain management and quality of life.

Who should consider this trial

Good fit: Ideal candidates include adults with cancer pain who have a life expectancy of more than three months and can communicate effectively.

Not a fit: Patients scheduled for surgery within the next three months or those with severe uncontrolled medical conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve pain management and quality of life for cancer patients.

How similar studies have performed: Other studies have shown promising results with pain neuroscience education, indicating its potential effectiveness in managing chronic pain.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with a life expectancy of more than three months (Karnofski Scales (KPS), Eastern Cooperative Oncology Group Scale (ECOG), survival prognosis PAP score, Palliative Prognosis Index PPI).
* Acceptance of informed consent.
* Educational level (high school diploma).
* No pain hospitalizations in the previous month
* Capable of establishing a team communication process
* at least 21 points on the MOCA scale for preserved cognitive function
* Understanding of the Spanish language.

Exclusion Criteria:

* Surgery scheduled within the next three months
* Visual and auditory sensory system deficiency (deafness or blindness).
* The presence of a recent traumatic injury
* Atrial or ventricular arrhythmias that are uncontrolled.
* Aortic aneurysm dissection
* Aortic stenosis severe
* Endocarditis or pericarditis that is acute
* Uncontrollable hypertension
* Thromboembolic disease, acute.
* Acute severe heart failure
* Acute severe respiratory failure
* Fracture within the last month

Where this trial is running

Iquique and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cancer PainPain Neuroscience educationCancer painPaliative therapyNeoplasm
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.