Pain management for chronic pancreatitis using endoscopic ultrasound techniques
Official title: Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis, Database Repository
Run by Indiana University · NCT04403074 · Data updated 2026-11-12
This study is testing a new way to manage pain for people with chronic pancreatitis by using a special ultrasound technique to block pain signals.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 35 (estimated) |
| Sponsor | Indiana University Academic / other |
| Locations | 1 site (Indianapolis, Indiana) |
| Status | Recruiting |
| Started | October 20, 2017 |
| Main results expected | October 20, 2029 |
| Study ends | October 20, 2029 |
| Registry record updated | February 18, 2026 |
| Trial ID | NCT04403074 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who are referred for pain treatment related to chronic pancreatitis.
✕Probably not a fit
Patients under 18 years of age or those without chronic pancreatitis will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to collect data on the effectiveness of endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) as a pain management technique for patients suffering from chronic pancreatitis. Chronic pancreatitis is associated with severe abdominal pain, and traditional pain management methods often involve narcotics, which can lead to adverse effects and dependency. The study will track the outcomes of patients undergoing EUS-CPN, which involves injecting a neurolytic agent to inhibit pain signals from the celiac plexus. By evaluating this approach, the study seeks to provide insights into alternative pain management strategies for chronic pancreatitis.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain management for patients with chronic pancreatitis, reducing reliance on narcotics.
How similar studies have gone: Previous studies have shown that celiac plexus neurolysis is a safe and effective method for pain management in chronic pancreatitis, indicating potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older * Referral for the treatment of pain related to chronic pancreatitis Exclusion Criteria: * Less than 18 years of age * Absence of chronic pancreatitis
Where it's running
-
Indiana University Hospital
Indianapolis, Indiana, United States Recruiting
Study contacts
- Principal investigator: Mo A, MD — Indiana University
- Study coordinator: Mohammad Al-Haddad
- Email: moalhadd@iu.edu
- Phone: 3179440980
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.