Clinical trial Recruiting at 1 site Observational Ages 18 and up

Pain management for chronic pancreatitis using endoscopic ultrasound techniques

Official title: Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis, Database Repository

Run by Indiana University · NCT04403074 · Data updated 2026-11-12

This study is testing a new way to manage pain for people with chronic pancreatitis by using a special ultrasound technique to block pain signals.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment35 (estimated)
SponsorIndiana University
Academic / other
Locations1 site (Indianapolis, Indiana)
StatusRecruiting
StartedOctober 20, 2017
Main results expectedOctober 20, 2029
Study endsOctober 20, 2029
Registry record updatedFebruary 18, 2026
Trial IDNCT04403074 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who are referred for pain treatment related to chronic pancreatitis.

Probably not a fit

Patients under 18 years of age or those without chronic pancreatitis will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to collect data on the effectiveness of endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) as a pain management technique for patients suffering from chronic pancreatitis. Chronic pancreatitis is associated with severe abdominal pain, and traditional pain management methods often involve narcotics, which can lead to adverse effects and dependency. The study will track the outcomes of patients undergoing EUS-CPN, which involves injecting a neurolytic agent to inhibit pain signals from the celiac plexus. By evaluating this approach, the study seeks to provide insights into alternative pain management strategies for chronic pancreatitis.

Why it matters

Potential benefit: If successful, this approach could significantly improve pain management for patients with chronic pancreatitis, reducing reliance on narcotics.

How similar studies have gone: Previous studies have shown that celiac plexus neurolysis is a safe and effective method for pain management in chronic pancreatitis, indicating potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years of age or older
* Referral for the treatment of pain related to chronic pancreatitis

Exclusion Criteria:

* Less than 18 years of age
* Absence of chronic pancreatitis

Where it's running

  • Indiana University Hospital
    Indianapolis, Indiana, United States
    Recruiting

Study contacts

  • Principal investigator: Mo A, MD — Indiana University
  • Study coordinator: Mohammad Al-Haddad
  • Email: moalhadd@iu.edu
  • Phone: 3179440980

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.