Clinical trial Recruiting at 3 sites Interventional Ages 18 and up

Pain education program for chronic musculoskeletal pain

Official title: Keeping It Simple Study (KISS) - Pain Science Education for Patients With Chronic Musculoskeletal Pain Undergoing Community-based Rehabilitation: A Multicenter Randomized Controlled Trial

Run by Aalborg University · NCT06297447 · Data updated 2026-11-12

This study tests if a new pain education program can help adults with long-lasting musculoskeletal pain manage their pain better and improve their quality of life.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorAalborg University
Academic / other
Locations3 sites (Holbæk, Region Sjælland and 2 other locations)
StatusRecruiting
StartedMarch 11, 2024
Main results expectedDecember 31, 2025
Study endsDecember 2026
Registry record updatedDecember 27, 2024
Trial IDNCT06297447 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with chronic musculoskeletal pain referred for rehabilitation in specific municipalities in Denmark.

Probably not a fit

Patients with cognitive deficits, serious pathologies, or those unable to cooperate may not benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The KISS project aims to evaluate the effectiveness of a pain neuroscience education program (PNE4Adults) on rehabilitation outcomes for patients suffering from chronic musculoskeletal pain. This program addresses maladaptive beliefs and psychological factors associated with chronic pain, which can hinder recovery. By combining pain science education with usual care, the study seeks to improve patients' pain management, self-efficacy, and overall quality of life. The study is conducted in specific municipalities in Denmark, targeting adults with chronic pain lasting more than three months.

Why it matters

Potential benefit: If successful, this program could significantly improve pain management and quality of life for patients with chronic musculoskeletal pain.

How similar studies have gone: Previous studies have shown that pain science education can lead to meaningful improvements in pain management and rehabilitation outcomes, indicating a promising approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients referred for rehabilitation in the municipalities Køge, Holbæk, and Solrød
* With chronic (\>3 months) musculoskeletal pain.
* Adult patients (≥18 years) - no upper limit
* Able to understand, speak, and write Danish.

Exclusion Criteria:

* Known cognitive deficits (e.g., dementia).
* Diagnosed with cancer or other serious pathologies, e.g., cauda equina.
* Pregnancy
* Drug addiction defined as the use of cannabis, opioids, or other drugs.
* Neurologic or psychiatric diagnoses that hinder participation, e.g., stroke and borderline.
* Lack of ability to cooperate.

Where it's running

  • Træningsenheden, Holbæk Municipality
    Holbæk, Region Sjælland, Denmark
    Recruiting
  • Træningsenheden, Køge Municipality
    Køge, Region Sjælland, Denmark
    Recruiting
  • Genoptræningscenteret, Solrød Municipality
    Solrød Strand, Region Sjælland, Denmark
    Recruiting

Study contacts

  • Principal investigator: Bettina Eiger, PhD-student — Aalborg University
  • Study coordinator: Bettina Eiger, PhD-student
  • Email: bettinae@hst.aau.dk
  • Phone: +4522988906

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.