Clinical trial Recruiting at 1 site Observational

Outcomes of adults with cirrhosis admitted to the general ICU (2014–2024)

Official title: Prognosis of Cirrhotic Patients Admitted to the General Intensive Care Unit Between 2014 and 2024: a Regional Retrospective Multicentre Cohort Study

Run by Centre Hospitalier Universitaire de Besancon · NCT06948565 · Data updated 2026-11-12

This project will see if adults with cirrhosis admitted to the ICU from 2014 to 2024 had better survival, access to liver transplantation, and ICU care practices than reported before 2014.

More Cirrhosis trials

Quick facts

Study typeObservational
SexAll
Enrollment500 (estimated)
SponsorCentre Hospitalier Universitaire de Besancon
Academic / other
Locations1 site (Besançon)
StatusRecruiting
StartedAugust 8, 2025
Main results expectedDecember 2025
Study endsDecember 2026
Registry record updatedAugust 11, 2025
Trial IDNCT06948565 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (age ≥18) with clinically or histologically confirmed cirrhosis who were admitted to the general intensive care unit at the participating hospitals between January 2014 and December 2024.

Probably not a fit

Patients under 18, those without cirrhosis, or patients treated outside the participating hospital network would not be included and would not directly benefit from this analysis.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a regional retrospective multicentre cohort analysis of adult patients with cirrhosis admitted to general intensive care units between January 2014 and December 2024. Medical records from a tertiary centre (CHU de Besançon) and affiliated primary hospitals will be reviewed for admission severity, ICU interventions, application of guideline-based practices, access to liver transplantation, and outcomes including survival. The analysis will compare current outcomes and care practices with data reported in the literature prior to 2014 and will look for variability in patient phenotype and outcomes related to centre resources. No prospective interventions are planned; all adults with clinically or histologically confirmed cirrhosis admitted during the period are eligible for inclusion.

Why it matters

Potential benefit: If successful, the findings could identify care practices that improve survival and transplant access and guide better ICU management for people with cirrhosis.

How similar studies have gone: Previous retrospective cohort studies, including the investigators' earlier pre-2014 publication, have reported improved ICU survival and transplant access for some cirrhotic populations, but results vary by region and centre.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patients with cirrhosis over 18 years of age (cirrhosis either histologically proven or diagnosed by hepatologists according to clinical, biological and ultrasound criteria) admitted to intensive care between January 2014 and December 2024.

Exclusion Criteria:

None

Where it's running

  • CHU de Besançon
    Besançon, France
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.