Optimizing treatment for ovarian cancer using patient samples
Official title: Systems Oncology Approach to Optimize Ovarian Cancer Treatment
Run by University of Helsinki · NCT06117384 · Data updated 2026-11-12
This study is trying to find better treatments for ovarian cancer by looking at samples from patients' tumors and blood to understand why some treatments don't work.
Quick facts
| Study type | Observational |
|---|---|
| Sex | Women only |
| Enrollment | 500 (estimated) |
| Sponsor | University of Helsinki Academic / other |
| Locations | 1 site (Helsinki) |
| Status | Recruiting |
| Started | January 1, 2022 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | November 7, 2023 |
| Trial ID | NCT06117384 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with ovarian cancer who have available tumor tissue or blood samples.
✕Probably not a fit
Patients who are unable to consent to the study will not benefit from this research.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to identify effective therapeutic strategies for ovarian cancer by analyzing tumor, ascites, and blood samples from patients. It employs advanced sequencing techniques and functional assays to explore the mechanisms of chemoresistance in ovarian cancer. By systematically collecting and interpreting molecular, functional, and clinical data, the study seeks to uncover new treatment options for patients suffering from this condition.
Why it matters
Potential benefit: If successful, this study could lead to more effective treatment strategies for ovarian cancer patients.
How similar studies have gone: Other studies utilizing similar biomolecular profiling approaches have shown promise in identifying effective treatments for various cancers.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients diagnosed with ovarian cancer * Available tumor tissue/blood samples Exclusion Criteria: * Inability to consent to the study
Where it's running
-
Helsinki University and Helsinki University Hospital
Helsinki, Finland Recruiting
Study contacts
- Principal investigator: Anniina Färkkilä, MD PhD — Helsinki University Central Hospital
- Study coordinator: Anniina Färkkilä, MD PhD
- Email: anniina.farkkila@helsinki.fi
- Phone: +358504272060
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
CG-7321: a first-in-human test in advanced solid tumors
We’re testing CG-7321 alone and with fulvestrant to see if it’s safe and tolerable in adults with advanced solid tumors.
-
CR-002 study in adults with advanced solid tumors
This trial tests CR-002 as a single therapy to see if it is safe and tolerable in adults with locally advanced or metastatic solid tumors
-
VT-101 in Advanced Ovarian Cancer: early safety study in adults
This early-phase trial tests VT-101 in adult women with advanced, recurrent, or relapsed epithelial ovarian cancer to see if it is safe, how the body handles it, and whether there are any initial signs of activity.
-
Methylation markers in self-samples to help detect gynecological cancers
This study tests whether self-collected urine and vaginal samples can reveal DNA methylation or other genetic markers that indicate endometrial, ovarian, vulvar, or vaginal cancers in women who are at risk or have postmenopausal bleeding.
-
Radiotherapy for gynecologic cancer with up to 10 metastatic sites
This registry follows adults with gynecologic cancer who have 1 to 10 active metastatic lesions and are treated with radiotherapy as part of routine care to see how such treatments work in real-world settings.
-
EHR-based approach to boost HBOC genetic testing in at-risk women
A new EHR tool-based program tests whether computer prompts and real patient resources can help more women with family histories of breast or ovarian cancer get HBOC genetic testing.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.