Optimizing preoperative nutrition and fasting for total knee replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will compare an ERAS-based preoperative nutrition education and fasting protocol to standard preoperative care in adults undergoing elective total knee arthroplasty. The intervention provides specific guidance on food and clear-liquid timing in the 24 hours before surgery and structured hydration and education based on ERAS guidelines. Participants will be randomly assigned at Acıbadem Altunizade Hospital and outcomes will include postoperative hydration status and the incidence of nausea and vomiting during the immediate postoperative period. The trial enrolls adults able to consent who are expected to remain hospitalized at least 48 hours after surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Inclusion Criteria:
* Adults aged 18 years and older.
* Patients scheduled for elective total knee arthroplasty.
* Patients expected to be hospitalized for at least 48 hours postoperatively.
* Ability to communicate verbally and provide informed consent.
* Patients with adequate cognitive and neurological capacity to understand study procedures.

Exclusion Criteria:

* Presence of any chronic disease requiring fluid restriction.
* Diagnosed cognitive impairment or psychiatric disorders affecting comprehension (e.g., Alzheimer's disease, dementia, psychotic disorders).
* Acute conditions causing dehydration in the preoperative period (e.g., vomiting, diarrhea, excessive fluid loss).
* Intraoperative complications requiring intensive care unit admission.
* Postoperative follow-up shorter than 48 hours due to early discharge or transfer to another clinic.

Where it's running

• Acıbadem Health Group Atakent Hospital
  Istanbul, Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Nermin Ocaktan, PhD — Acibadem University
• Study coordinator: Nermin Ocaktan, PhD
• Email: nermin.ocaktan@acibadem.edu.tr
• Phone: +905337373306

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.