Optimizing new MRI scan sequences on a dedicated imaging scanner
Official title: Test and Optimization of New Specific MRI Sequences on an Imager Dedicated to Research
Run by University Hospital, Bordeaux · NCT03674645 · Data updated 2026-11-12
We will test new MRI scan methods in healthy adults to get clearer images with shorter scan times.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | University Hospital, Bordeaux Academic / other |
| Locations | 1 site (Pessac) |
| Status | Recruiting |
| Started | September 19, 2018 |
| Main results expected | September 2028 |
| Study ends | September 2028 |
| Registry record updated | March 6, 2026 |
| Trial ID | NCT03674645 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy adults aged 18 and over without contraindications to MRI who can provide informed consent are the intended participants.
✕Probably not a fit
People who are pregnant or breastfeeding, have MRI contraindications or conditions that interfere with imaging, are under guardianship, or cannot consent are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will translate MRI sequences first developed on phantoms and in animals to a human imaging scanner and test them in healthy volunteers. Each volunteer will undergo specific MRI acquisitions at CHU de Bordeaux where operators will adjust and optimize acquisition parameters to improve spatial resolution, specificity, and reduce scan time. The goal is to identify practical, reproducible settings for each new sequence and to validate their technical performance in people without known disease. Results will be used to define clinically relevant examination protocols for future diagnostic and monitoring use.
Why it matters
Potential benefit: If successful, the optimized sequences could produce higher-resolution, more specific MRI images in less time, potentially improving diagnosis and therapy monitoring.
How similar studies have gone: Similar MRI sequence development has shown technical success in phantom and animal work and in prior technical human studies, though human protocol optimization continues to be refined.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy volunteers (over 18 yo), * Male or female, * Affiliated to social security, * Without any contraindication to MRI exam and who will have signed a written inform consent. Exclusion Criteria: * Individuals deprived of liberty, * Under guardianship or curatorship, * Persons with known disease which could disturb MRI acquisition or with absolute or relative contraindication to an MRI examination * Pregnant women, * Breastfeeding women, * Women without effective contraception, * Participants who refused to be informed of the possible discovery of a significant anomaly, * Persons involved in an interventional study with a drug or an implantable device.
Where it's running
-
CHU de Bordeaux
Pessac, France Recruiting
Study contacts
- Principal investigator: Hubert COCHET, MD — University Hospital, Bordeaux
- Study coordinator: Hubert COCHET, MD
- Email: hubert.cochet@chu-bordeaux.fr
- Phone: (0)557675613
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.