Optimizing MRI techniques for studying memory disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on enhancing MRI sequences used to investigate neurodegenerative diseases and memory disorders. The Inserm NeuroPresage team aims to utilize a new 3T MRI camera to improve image quality and reduce acquisition time. By testing various MRI sequences, the study seeks to optimize these techniques for future research on cognitive deficits and early diagnosis in patients. The findings could lead to better diagnostic tools and understanding of memory-related conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy volunteers of legal age
* Affiliation with a social security scheme or beneficiary of such a scheme
* Signing of the protocol informed consent
* For women of childbearing age or capacity, a urine pregnancy test before inclusion

Exclusion Criteria:

* Protected persons in accordance with articles L. 1121-5 to L.1121-8 of the Public Health Code: protected adults, pregnant and nursing women
* Presence of contraindications to MRI examination without contrast agents injection
* Presence of a chronic neurological or psychiatric condition (including substance use disorder)
* History of brain disease (vascular, degenerative, malformative, tumour, or head trauma with loss of consciousness for more than one hour)
* Current or recent use of medications that may interfere with imaging (psychotropic drugs, antihistamines with anticholinergic action, antiparkinsonian drugs, benzodiazepines including muscle relaxants, long-term steroidal anti-inflammatory drugs, antiepileptic drugs, central painkillers)

Where it's running

• GIP Cyceron
  Caen, France Recruiting

Study contacts

• Principal investigator: Nicolas Cabé, MD, PhD — CHU Caen Normandie
• Study coordinator: Géraldine Poisnel, PhD
• Email: poisnel@cyceron.fr
• Phone: 0231470206

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.