Optimizing esophageal pressure measurement in pediatric patients on mechanical ventilation
Decremental Esophageal Catheter Filling Volume Titration For Esophageal Pressure Measurement
This study is testing two ways to fill a tube used to measure pressure in the lungs of children on breathing machines to see which method gives more accurate results and helps improve their care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 27 (estimated) |
| Ages | 1 Month to 18 Years |
| Sex | All |
| Sponsor | Dr. Behcet Uz Children's Hospital Academic / other |
| Locations | 4 sites (Aydin and 3 other locations) |
| Trial ID | NCT06051292 on ClinicalTrials.gov |
What this trial studies
This study focuses on improving the accuracy of transpulmonary pressure measurement in pediatric patients experiencing respiratory distress. It compares two methods of esophageal catheter filling volume titration to enhance the reliability of esophageal pressure measurements. The goal is to minimize errors associated with underfilling or overfilling the catheter, which can impact patient safety and treatment efficacy. By refining these measurement techniques, the study aims to provide better management strategies for pediatric acute respiratory distress syndrome.
Who should consider this trial
Good fit: Ideal candidates include pediatric patients aged 1 month to 18 years who require mechanical ventilation support.
Not a fit: Patients who are eligible for extubation or modification of ventilation settings within the next two hours may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate monitoring and management of pediatric patients with respiratory distress, improving their treatment outcomes.
How similar studies have performed: While the specific approach of this study may be novel, similar studies have indicated the importance of accurate transpulmonary pressure measurement in improving patient outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pediatric patients between 1 months and 18 years * Patients need mechanical ventilation support without modification of ventilation settings within the upcoming 2 hours * Informed consent was signed by next of kin * Requiring esophageal catheter application Exclusion Criteria: * Patients eligible for extubation or modification of ventilation settings within the upcoming 2 hours * Patient included in another interventional study in the last 30 days * Patients unable to undergo esophageal catheter insertion due to congenital or acquired pathologies * Patient included in another interventional research study under consent * Patient already enrolled in the present study in a previous episode of acute respiratory failure
Where this trial is running
Aydin and 3 other locations
- Aydin Obstetric and pediatrics Hospital — Aydin, Turkey (Türkiye) (Recruiting)
- Erzurum Regional Research and Training Hospital — Erzurum, Turkey (Türkiye) (Recruiting)
- Cam Sakura Research and Training Hospital — Istanbul, Turkey (Türkiye) (Recruiting)
- The Health Sciences University Izmir Behçet Uz Child Health and Diseases Research and Training Hospital — Izmir, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Hasan Agin, Professor
- Email: hasanagin@gmail.com
- Phone: 05362013162
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.