Optimizing brain stimulation for epilepsy treatment
Optimizing Brain Stimulation Parameters
This study is testing whether low or high frequency brain stimulation can help people with epilepsy control their seizures better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 6 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT06617845 on ClinicalTrials.gov |
What this trial studies
This study aims to determine the most effective stimulation parameters for patients with epilepsy using Deep Brain Stimulation (DBS) targeting the Anterior Nucleus of the Thalamus (ANT). It will compare the effectiveness of low frequency versus high frequency stimulation to identify which approach yields better outcomes for seizure control. Patients who have already received a brain stimulation device will be monitored over a period of 6-8 months to assess the impact of these different stimulation settings.
Who should consider this trial
Good fit: Ideal candidates for this study are patients who have been implanted with a brain stimulation device targeting the anterior nucleus of the thalamus.
Not a fit: Patients who are not expected to have clinical follow-up during the initial 6-8 months after implant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved seizure control for patients with epilepsy through optimized brain stimulation techniques.
How similar studies have performed: Other studies have explored brain stimulation for epilepsy, but this specific approach to optimizing stimulation parameters is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who are implanted with a brain stimulation device targeting the anterior nucleus of the thalamus per Mayo Clinic standard of care Exclusion Criteria: * Patients for whom clinical follow-up is not expected during the initial 6-8 months following implant
Where this trial is running
Rochester, Minnesota
- Mayo Clinic Rochester — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Study coordinator: Amy Headlee
- Email: headlee.amy@mayo.edu
- Phone: 507-538-4107
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.