Optimizing a smoking cessation program for people living with HIV
Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care
This study is trying to find the best way to help people living with HIV quit smoking by using a mix of support methods like counseling, mentoring, and text reminders.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | New York University Academic / other |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT06598397 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance smoking cessation outcomes for smokers living with HIV by implementing a multiphase optimization strategy (MOST) that addresses both patient and clinical care barriers. The intervention includes components such as Motivational Interviewing, Peer Mentoring, Text Messaging, and Combination Nicotine Replacement Therapy, which have shown potential but are underutilized. The study will evaluate the effectiveness, acceptability, and feasibility of these interventions within HIV clinical care settings to develop a cost-effective and scalable smoking cessation package. By targeting a diverse population of smokers living with HIV, the study seeks to improve overall health outcomes and reduce smoking rates in this vulnerable group.
Who should consider this trial
Good fit: Ideal candidates for this study are HIV-positive individuals aged 18 or older who smoke at least 5 cigarettes per day and are engaged in HIV clinical care.
Not a fit: Patients who are currently using tobacco cessation medications or participating in other smoking cessation programs may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve smoking cessation rates among smokers living with HIV, leading to better health outcomes.
How similar studies have performed: While components of the intervention have shown promise in previous research, this specific optimization approach has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Status as HIV+ * Age 18 or older * Currently smokes ≥ 5 CPD, on average, in past month * Positive for salivary cotinine * Able to understand the nature of the study and the consenting process * Is engaged in HIV clinical care * Living in larger NYC metropolitan area currently and for the next 6-8 months Exclusion Criteria: * Suffers from any medical condition or contraindication precluding use of nicotine replacement therapy * Current use of any tobacco cessation medications (varenicline, NRT patch, nicotine gum, lozenge, spray or inhaler, or bupropion) * Currently participating in a smoking cessation program * Pregnant or nursing and plans to be in next 6 months * Has schizophrenia/schizo-affective disorder * Does not have a functioning mobile phone that can receive text messages
Where this trial is running
New York, New York
- New York University School of Global Public Health — New York, New York, United States (Recruiting)
Study contacts
- Study coordinator: Jennifer Cantrell, DrPH, MPA
- Email: jennifer.cantrell@nyu.edu
- Phone: 212-998-5797
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.