Optimizing a smoking cessation program for people living with HIV

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance smoking cessation outcomes for smokers living with HIV by implementing a multiphase optimization strategy (MOST) that addresses both patient and clinical care barriers. The intervention includes components such as Motivational Interviewing, Peer Mentoring, Text Messaging, and Combination Nicotine Replacement Therapy, which have shown potential but are underutilized. The study will evaluate the effectiveness, acceptability, and feasibility of these interventions within HIV clinical care settings to develop a cost-effective and scalable smoking cessation package. By targeting a diverse population of smokers living with HIV, the study seeks to improve overall health outcomes and reduce smoking rates in this vulnerable group.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Status as HIV+
* Age 18 or older
* Currently smokes ≥ 5 CPD, on average, in past month
* Positive for salivary cotinine
* Able to understand the nature of the study and the consenting process
* Is engaged in HIV clinical care
* Living in larger NYC metropolitan area currently and for the next 6-8 months

Exclusion Criteria:

* Suffers from any medical condition or contraindication precluding use of nicotine replacement therapy
* Current use of any tobacco cessation medications (varenicline, NRT patch, nicotine gum, lozenge, spray or inhaler, or bupropion)
* Currently participating in a smoking cessation program
* Pregnant or nursing and plans to be in next 6 months
* Has schizophrenia/schizo-affective disorder
* Does not have a functioning mobile phone that can receive text messages

Where it's running

• New York University School of Global Public Health
  New York, New York, United States Recruiting

Study contacts

• Study coordinator: Jennifer Cantrell, DrPH, MPA
• Email: jennifer.cantrell@nyu.edu
• Phone: 212-998-5797

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Quitting Matters: a smoking quit program for people living with HIV

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• Smoky Futures: Danish Adolescent Nicotine Use over Time

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  Recruiting University of Southern Denmark · Copenhagen · NCT07910331

• Nicotine Orodispersible Tablet to Relieve Cravings in Smokers

  A nicotine mint orodispersible tablet is tested vs placebo to see if it quickly eases the urge to smoke in adult cigarette smokers.

  Recruiting Phase 2 Kenvue Brands LLC · Mississauga, Ontario · NCT07893158

• Optimizing when weekly chatbot reminders go out to people using a chatbot for quitting smoking

  This study tests whether sending weekly reminders at different times helps people stay engaged with a chatbot smoking-cessation service.

  Recruiting The University of Hong Kong · Hong Kong · NCT07826884

• NMDA and Sigma-1 combination therapy for smoking cessation with AXS-05

  This phase 3 trial tests whether AXS-05 can help adults quit smoking better than placebo or bupropion.

  Recruiting at 28 sites Phase 3 Axsome Therapeutics, Inc. · Phoenix, Arizona and 27 other locations · NCT07766655

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.