Optimal ATP settings for new ICDs in heart disease patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pragmatic, cluster-randomized trial compares two ATP programming strategies (Burst vs Ramp) for ventricular tachyarrhythmias in patients receiving a new ICD. Hospitals are randomized to one strategy for four months at a time, with the chosen approach followed for the device’s lifetime unless reprogrammed. The study focuses on ATP delivery in the VT zone defined as roughly 180–249 (up to 269) beats per minute. Outcomes are driven by the occurrence of ATP events over time, aiming to determine which setting reduces VT-related interventions. Participation is offered to patients undergoing ICD implantation for primary or secondary protection, with opt-out allowed.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- ICD implantation for primary or secondary prophylactic indication

Exclusion Criteria:

* None
* Patients can actively opt out of participation in the study

Where it's running

• The Heart Center, Rigshospitalet
  Copenhagen, Dr., Denmark Recruiting

Study contacts

• Study coordinator: Bo G Winkel, MD, PhD
• Email: bo.winkel@regionh.dk
• Phone: +4535459759

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.