Upper-extremity exercise options for people with heart failure and implanted devices

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares high-intensity interval, moderate-intensity continuous, and lower-extremity aerobic programs to determine the best way to improve upper-extremity functional capacity in patients with heart failure and CIED/CRT devices. It uses a randomized or controlled approach to compare different training protocols and their impact on arm function. Eligible participants are adults with heart failure, NYHA class II-III, who have had device implantation and meet safety criteria. The study analyzes whether upper-extremity training offers advantages over lower-extremity training alone. Results could guide tailored cardiac rehabilitation for this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18 and over with heart failure who are receiving Implantable Cardioverter Defibrillator (ICD) or Cardiac Resynchronization Therapy (CRT)
* At least 3 months have passed since device implantation and there have been no complications at the last device control
* Being in New York Heart Association (NYHA) Class II-III
* Patients without cooperation problems
* Patients who volunteer to participate in the study

Exclusion Criteria:

* Patients who have previously participated in a cardiac rehabilitation program and those who have completed less than 1 year since the program,
* Patients with a primary diagnosis of cardiomyopathy and those with heart failure secondary to cardiomyopathy,
* Patients with a history of shoulder pathologies that may restrict upper extremity movement before device implantation (such as severe pain around the shoulder, edema, or shoulder dislocation that restricts upper extremity movement),
* Patients with a history of shoulder surgery (patients with limitations in range of motion),
* Patients who have undergone mastectomy on the affected side or a cerebrovascular event resulting in arm involvement,
* Patients with decompensated heart failure,
* Patients with a history of ICD-incompatible shock,
* Patients with a history of unstable angina pectoris, acute myocardial infarction, or cardiac surgery within the last 3 months,
* Patients who have experienced acute atrial fibrillation, ventricular tachycardia, and ventricular fibrillation within the last 3 months,
* Patients with actively treated malignancy or collagen tissue disease receiving systemic steroids
* Patients with chronic kidney disease undergoing dialysis where volume load is unstable,
* Persistent ventricular arrhythmias during baseline cardiopulmonary exercise testing.

Where it's running

• Hitit University Erol Olcok Training and Research Hospital, Cardiac Rehabilitation Unit
  Çorum, Turkey (Türkiye) Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.