Opioid-free anesthesia for duodenopancreatic surgery by laparotomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study examines an opioid-free anesthesia approach as an alternative to standard opioid-based anesthesia for patients undergoing duodenopancreatic surgery via laparotomy. By using non-opioid analgesics, co-analgesics, and regional/local anesthesia techniques, the protocol aims to maintain adequate analgesia while reducing opioid-related side effects. The design focuses on applying a multimodal, balanced anesthesia strategy to minimize opioid exposure and associated complications such as PONV and constipation. Eligible participants are adults 18-80 with ASA II-III undergoing pancreaticoduodenal surgery and who can consent to regional anesthesia and participation. Outcomes of interest include pain control, postoperative opioid consumption, and incidence of opioid-related adverse effects.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18-80 years
* ASA II and III
* Patient consent to the proposed regional anesthesia
* Patient consent to participate in the study
* Surgical procedure in the pancreaticoduodenal area by laparotomy Exclusion criterion
* Patient refusal to participate in the study
* Inability to operate the PCA pump
* Lack of understanding of the NRS scale
* Hypersensitivity to anesthetics
* First- or second-degree heart block.

Where it's running

• Department of Intensive Interdisciplinary Care, Collegium Medicum, Jagiellonian University
  Krakow, Lesser Poland Voivodeship, Poland Recruiting

Study contacts

• Study coordinator: Tomasz Skladzien, phd md
• Email: t.skladzien@interia.pl
• Phone: +48 12 4001800

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.