Opioid-free anesthesia for abdominal aortic aneurysm repair

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of an opioid-free anesthesia-analgesia strategy on surgical stress and postoperative outcomes in patients undergoing elective open abdominal aortic aneurysm repair. The study compares traditional opioid-based anesthesia with a multimodal approach that utilizes various anesthetic and analgesic agents to minimize opioid use. By focusing on reducing the inflammatory response associated with surgical trauma, the trial aims to improve patient recovery and reduce complications. The research is conducted at the University of Crete, involving patients aged 40 to 85 who meet specific eligibility criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patient Consent
2. Age between 40 and 85 years old
3. Patients undergoing Elective Open Abdominal Aortic Infrarenal Aneurysm Repair

Exclusion Criteria:

1. Immunocompromised patients
2. Patients with active infection
3. Reoperation on the aorta
4. Inflammatory bowel Disease
5. Malignancy
6. Chronic Inflammatory conditions (e.g. Rheymatoid arthritis, Psoriatic arthritis)
7. Chronic corticosteroid or immunosuppressive drug use
8. Intraoperative transfusion with \>2 units of packed Red Blood Cells

Where it's running

• University of Crete
  Heraklion, Crete, Greece Recruiting

Study contacts

• Study coordinator: George Papastratigakis, MD
• Email: papastratigakisg@gmail.com
• Phone: 00306979056672

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.