Opioid-free anesthesia as an option for people having laparoscopic pancreatic surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this study, adults undergoing laparoscopic peripheral pancreatic resection are randomly assigned to either opioid-free anesthesia or balanced anesthesia with opioids. Postoperative pain, total oxycodone use, and pain scores over the first 48 hours will be recorded, along with nausea, vomiting, adverse drug reactions, and impact on persistent pain. Quality of life and patient-reported analgesia satisfaction will be assessed with QOR-15 and PQA-10 on day 7. The goal is to determine if removing intraoperative opioids reduces opioid consumption by about 30% without compromising analgesia or safety.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient consent to participate in the study
* Qualified for laparoscopic peripheral pancreatic resection
* Age 18-80 years
* ASA II and III

Exclusion Criteria:

* Patient refusal to participate in the study
* Inability to operate a PCA pump
* Lack of understanding of the NRS scale
* Hypersensitivity to anesthetics
* First- or second-degree heart block.

Where it's running

• Department of Intensive Interdisciplinary Care, Collegium Medicum, Jagiellonian University
  Krakow, Lesser Poland Voivodeship, Poland Recruiting
• University Hospital in Cracow
  Krakow, Lesser Poland Voivodeship, Poland Recruiting

Study contacts

• Study coordinator: Michal Cicio, MD
• Email: michal.cicio@uj.edu.pl
• Phone: 124001800

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.