Online intervention for postpartum depression

Maternal Well-being in the Postnatal Stage: Evaluation of Cognitive Biases and Validation of a Psychological Intervention

Not applicable Interventional Universidad Complutense de Madrid · NCT05676918

This study is testing an online program to help women with postpartum depression by comparing two different types of support: one focused on changing thoughts and behaviors and the other on boosting happiness and well-being.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment98 (estimated)
Ages18 Years and up
SexFemale
SponsorUniversidad Complutense de Madrid Academic / other
Locations1 site (Madrid, Pozuelo de Alarcón)
Trial IDNCT05676918 on ClinicalTrials.gov

What this trial studies

This study aims to design and validate an online intervention to enhance well-being in women experiencing postpartum depression. Participants will be randomly assigned to either a Cognitive Behavioral Therapy (CBT) group or a Positive Psychology Intervention (PPI) group, with both groups receiving 10 weekly online sessions. The CBT group will focus on behavioral activation, cognitive restructuring, and interpersonal skills, while the PPI group will emphasize hedonic and eudaimonic well-being through validated positive interventions. The study follows NICE recommendations for treating depression and aims to compare the effectiveness of these two approaches.

Who should consider this trial

Good fit: Ideal candidates for this study are women who have given birth within the last year and are experiencing symptoms of postpartum depression.

Not a fit: Women who have recently given birth within the last month or those with serious mental disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the mental health and overall well-being of women suffering from postpartum depression.

How similar studies have performed: Previous studies have shown success with both Cognitive Behavioral Therapy and Positive Psychology interventions in treating depression, indicating that this approach is grounded in established methodologies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women who have been mothers in the last year

Exclusion Criteria:

* Women who have been mothers in the last month,
* Women who meet the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for substance abuse and/or dependence within 30 days prior to study participation,
* Women who have a serious mental disorder that makes it difficult to follow the protocol (e.g. serious neurocognitive problems or brain damage; schizophrenia and other psychotic disorders).

Where this trial is running

Madrid, Pozuelo de Alarcón

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postpartum DepressionPostpartum Disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.