Olfactory training for smell issues after COVID-19
L'entraînement Olfactif Comme Traitement De La Dysfonction Olfactive Post COVID-19
This study is testing if a special smell training program can help people who have trouble smelling after having COVID-19 feel better and improve their sense of smell.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Université du Québec à Trois-Rivières Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Trois-Rivières, Quebec) |
| Trial ID | NCT05384561 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of olfactory training as a treatment for persistent smell dysfunction following COVID-19 infection. Participants will be divided into two groups, each using a different set of scents for training over a 12-week period. The study will assess olfactory function through various tests and questionnaires before and after the training. The goal is to determine which set of scents is more effective in improving olfactory perception and reducing symptoms like parosmia and phantosmia.
Who should consider this trial
Good fit: Ideal candidates are individuals who have tested positive for COVID-19 and are experiencing persistent olfactory dysfunction.
Not a fit: Patients with pre-existing anosmia or hyposmia, chronic rhinosinusitis, or neurodegenerative diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the quality of life for patients suffering from smell impairments post-COVID-19.
How similar studies have performed: Previous studies have shown positive outcomes with olfactory training for post-infectious smell dysfunction, suggesting this approach is promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient diagnosed positive for COVID-19 with persistent olfactory dysfunction * Willing and able to provide written informed consent * Understand and read the French language * Have an internet connection and a working email address Exclusion Criteria: * Anosmia and hyposmia pre-covid-19 * Be known chronic rhinosinusitis with or without nasal polyposis * Have received radiotherapy or chemotherapy for Head and Neck Tumors * Have a diagnosis of Alzheimer's, Parkinson's, multiple sclerosis or any other neurodegenerative disease 5. Have a brain tumor or ENT diagnosis 6. History of naso-sinus surgery; 7. History of traumatic brain injury
Where this trial is running
Trois-Rivières, Quebec
- Université du Québec à Trois-Rivières — Trois-Rivières, Quebec, Canada (Recruiting)
Study contacts
- Principal investigator: Johannes A Frasnelli, PhD — Université du Québec à Trois-Rivières
- Study coordinator: Johannes A Frasnelli, PhD
- Email: johannes.a.frasnelli@uqtr.ca
- Phone: 18193765011
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.