Observing the progression of bicuspid aortic valve in Chinese patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather comprehensive epidemiological data on congenital bicuspid aortic valve (BAV) in China, where its prevalence may be higher than previously recognized. The study will analyze genetic backgrounds, pathological progression, and imaging characteristics of young patients diagnosed with BAV. Participants aged 14-60 will be monitored over time to understand disease progression and treatment outcomes, contributing to the identification of high-risk individuals. The findings may enhance clinical observation and management of BAV in the Chinese population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The patients were aged 14-60 years;
* Definitive diagnosis of BAV by imaging (echocardiography, aortic CTA, cardiac magnetic resonance, etc.)
* Patients were informed about the nature of the study and agreed to participate in all the terms of the study and signed an informed consent form approved by the ethics committee.

Exclusion Criteria:

* Poor patient compliance and inability to complete follow-up visits as required;
* Rheumatic heart valve disease, other organic valve disease.
* Hyperthyroidism, severe anemia, and other factors that significantly affect hemodynamics.
* Other circumstances that the researcher believes should be excluded.

Where it's running

• Ruijin hospital, Shanghai JiaoTong University School of Medicine
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Wenli Zhang, MD
• Email: zwl11929@rjh.com.cn
• Phone: +86 (021)64370045

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.