Observing sleep disorders in patients with neurodegenerative diseases
Official title: A Registered Observational Cohort Study on Neurodegenerative Associated With Sleep Disorder.
Run by Fujian Medical University Union Hospital · NCT05524922 · Data updated 2026-11-12
This study looks at how sleep problems affect people with neurodegenerative diseases to better understand their impact on thinking and memory.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 30 Years to 80 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Fujian Medical University Union Hospital Academic / other |
| Locations | 1 site (Fuzhou, Fujian) |
| Status | Recruiting |
| Started | September 1, 2021 |
| Main results expected | June 1, 2030 |
| Study ends | June 1, 2030 |
| Registry record updated | January 22, 2025 |
| Trial ID | NCT05524922 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals with a clinical diagnosis of a neurodegenerative disease who experience significant sleep disturbances.
✕Probably not a fit
Patients with other neurological disorders unrelated to neurodegenerative diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the relationship between sleep disorders and the progression of neurodegenerative diseases. It will collect data on clinical manifestations, imaging results, and biological markers associated with sleep disturbances in affected patients. The study focuses on individuals diagnosed with neurodegenerative disorders who experience various sleep-related issues, such as insomnia and excessive daytime sleepiness. By analyzing these factors, the study seeks to enhance understanding of how sleep disorders impact cognitive impairment in neurodegenerative conditions.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for sleep disorders in patients with neurodegenerative diseases, potentially enhancing their quality of life.
How similar studies have gone: While there is ongoing research into sleep disorders in neurodegenerative diseases, this specific observational approach may provide novel insights into their relationship.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. clinical diagnosis of neurodegenerative disease. 2. patients experience insomnia, excessive drowsiness, or confusion at night. 3. Patients experience frequent awakenings, daily sleep episodes, or nocturnal confusion. 4. The presence of one or more of the following characteristics: a. wandering at night with inappropriate activity; b. agitation, combativeness; c. confusion, disorientation, or marked delirium. 5. Polysomnographic monitoring showed the following two conditions: a. poor sleep efficiency, increased number and duration of awakenings; b. multiple sleep latency tests showed increased daytime sleepiness. 6. Presence of other medical symptoms that do not indicate the primary disease. 7. Other sleep disorders (e.g., periodic limb movement disorders, obstructive sleep apnea syndrome) may be present, but do not explain the patient 's main symptoms. 8. any of the above can be diagnosed Exclusion Criteria: 1. Patients with other neurological disorders. 2. Pregnant or lactating women.
Where it's running
-
Fujian Medical University Union Hospital
Fuzhou, Fujian, China Recruiting
Study contacts
- Study coordinator: Xiaodong Pan, Doctor
- Email: pxd77316@163.com
- Phone: 0591-86218341
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.