Observing lung cancer in never-smokers in the UK
An Observational Study of Predictors and Outcomes of Lung Cancer in Never-smokers in the UK
University College London Hospitals · NCT06575439
This study looks at lung cancer in people who have never smoked to see how we can find it earlier and understand what might cause it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 225 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University College London Hospitals (other) |
| Locations | 1 site (London) |
| Trial ID | NCT06575439 on ClinicalTrials.gov |
What this trial studies
This observational study aims to enhance early detection of lung cancer in adults who have never smoked more than 100 cigarettes. It will analyze participant demographics, co-morbidities, environmental exposures, and their pathways to diagnosis, including symptoms and treatment outcomes. The study will also assess various factors, both modifiable and non-modifiable, that may influence lung cancer in this population, utilizing environmental measures, blood tests, and genomic data. Participants will continue with their usual care throughout the study.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have been diagnosed or treated for primary lung cancer and have never smoked more than 100 cigarettes.
Not a fit: Patients who have ever smoked more than 100 cigarettes or have used nicotine replacement therapy will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection and treatment strategies for lung cancer in never-smokers.
How similar studies have performed: While there have been studies on lung cancer in smokers, this specific focus on never-smokers is relatively novel and less explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All adult participants from age of 18 who are diagnosed or treated with primary lung cancer through radiology or histology at any participating study site Exclusion Criteria: * Participants who have ever smoked cigarettes or tobacco will be excluded; this is defined as: * More than 100 cigarettes or 75g tobacco in their lifetime * Those who have received a prescription for nicotine replacement therapy * For prospective participants, those who cannot consent will be excluded
Where this trial is running
London
- University College London Hospital — London, United Kingdom (RECRUITING)
Study contacts
- Study coordinator: Neal Navani, PhD
- Email: n.navani@ucl.ac.uk
- Phone: 020 7679 2000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Lung Cancer