Observing brain responses to music and language in unconscious patients with acute brain injuries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to determine whether acute brain injury patients who are clinically unconscious but show brain activation in response to auditory stimuli, such as music and language, have improved recovery outcomes. The study will utilize electroencephalogram (EEG) testing to assess brain activity in these patients. Participants will include adults aged 18 and older who are admitted to the intensive care unit with a Glasgow Coma Scale score of less than 8. The research will also involve healthy volunteers for comparative analysis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

For ABI Participants

* ABI adult (18 years and older) patients who are admitted to the intensive care unit
* Unconscious with Glasgow Coma Scale (GCS) \<8 on presentation and unable to follow bedside commands.
* A negative COVID-19 test on arrival

For Healthy Volunteers:

* 18 years and older

Exclusion Criteria:

For All Participants:

* \<18 years of age
* Pregnant woman
* Patients with cardiac arrest on presentation

Where it's running

• Jackson Memorial Hospital
  Miami, Florida, United States Recruiting
• Columbia University
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Ayham Alkhachroum, MD — University of Miami
• Study coordinator: Ayham Alkhachroum, MD
• Email: axa2610@med.miami.edu
• Phone: (305) 243-3218

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.