Observational study on risk factors for progressive pulmonary fibrosis

A Multicenter Prospective Study of Risk Factors in Progressive Pulmonary Fibrosis

Qianfoshan Hospital · NCT05895409

This study looks at what factors might lead to worsening pulmonary fibrosis in people with interstitial lung disease to better understand the condition and its effects over time.

Quick facts

Study typeObservational
Enrollment610 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorQianfoshan Hospital (other)
Locations1 site (Jinan, Shandong)
Trial IDNCT05895409 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the risk factors, prevalence, and mortality associated with progressive pulmonary fibrosis (PPF) in patients with interstitial lung disease (ILD). Participants will undergo baseline assessments, including demographic data, medical history, and various lung function tests, along with blood sampling. Follow-up visits at 6 and 12 months will repeat these assessments to track changes over time. The study focuses on patients with radiological evidence of pulmonary fibrosis, excluding those with idiopathic pulmonary fibrosis.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-80 with interstitial lung disease and imaging features of pulmonary fibrosis.

Not a fit: Patients with idiopathic pulmonary fibrosis, pregnant or lactating women, and those with cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of progressive pulmonary fibrosis and inform better management strategies for patients with interstitial lung disease.

How similar studies have performed: While similar studies have explored risk factors in pulmonary fibrosis, this specific observational approach is less common and may provide novel insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18-80 years old
* Agree and sign the informed consent form
* Interstitial lung disease patients with imaging features of pulmonary fibrosis

Exclusion Criteria:

* Patients with idiopathic pulmonary fibrosis (IPF)
* Pregnant or lactating women
* mental illness or cognitive impairment
* participating in other clinical studies
* Unable to sign informed consent form

Where this trial is running

Jinan, Shandong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Interstitial Lung Disease, progressive pulmonary fibrosis

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.