Observational study on risk factors for progressive pulmonary fibrosis
Official title: A Multicenter Prospective Study of Risk Factors in Progressive Pulmonary Fibrosis
Run by Qianfoshan Hospital · NCT05895409 · Data updated 2026-11-12
This study looks at what factors might lead to worsening pulmonary fibrosis in people with interstitial lung disease to better understand the condition and its effects over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 610 (estimated) |
| Sponsor | Qianfoshan Hospital Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Status | Recruiting |
| Started | July 27, 2023 |
| Main results expected | June 1, 2026 |
| Study ends | June 1, 2028 |
| Registry record updated | November 18, 2023 |
| Trial ID | NCT05895409 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18-80 with interstitial lung disease and imaging features of pulmonary fibrosis.
✕Probably not a fit
Patients with idiopathic pulmonary fibrosis, pregnant or lactating women, and those with cognitive impairments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the risk factors, prevalence, and mortality associated with progressive pulmonary fibrosis (PPF) in patients with interstitial lung disease (ILD). Participants will undergo baseline assessments, including demographic data, medical history, and various lung function tests, along with blood sampling. Follow-up visits at 6 and 12 months will repeat these assessments to track changes over time. The study focuses on patients with radiological evidence of pulmonary fibrosis, excluding those with idiopathic pulmonary fibrosis.
Why it matters
Potential benefit: If successful, this study could enhance understanding of progressive pulmonary fibrosis and inform better management strategies for patients with interstitial lung disease.
How similar studies have gone: While similar studies have explored risk factors in pulmonary fibrosis, this specific observational approach is less common and may provide novel insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-80 years old * Agree and sign the informed consent form * Interstitial lung disease patients with imaging features of pulmonary fibrosis Exclusion Criteria: * Patients with idiopathic pulmonary fibrosis (IPF) * Pregnant or lactating women * mental illness or cognitive impairment * participating in other clinical studies * Unable to sign informed consent form
Where it's running
-
The First Affiliated Hospital of Shandong First Medical University
Jinan, Shandong, China Recruiting
Study contacts
- Study coordinator: zhi guo, Doctor
- Email: guozhi770217@163.com
- Phone: +8613853120761
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.