Clinical trial Recruiting at 1 site Observational Ages 18 to 80

Observational study on risk factors for progressive pulmonary fibrosis

Official title: A Multicenter Prospective Study of Risk Factors in Progressive Pulmonary Fibrosis

Run by Qianfoshan Hospital · NCT05895409 · Data updated 2026-11-12

This study looks at what factors might lead to worsening pulmonary fibrosis in people with interstitial lung disease to better understand the condition and its effects over time.

Quick facts

Study typeObservational
Ages18 Years to 80 Years
SexAll
Enrollment610 (estimated)
SponsorQianfoshan Hospital
Academic / other
Locations1 site (Jinan, Shandong)
StatusRecruiting
StartedJuly 27, 2023
Main results expectedJune 1, 2026
Study endsJune 1, 2028
Registry record updatedNovember 18, 2023
Trial IDNCT05895409 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18-80 with interstitial lung disease and imaging features of pulmonary fibrosis.

Probably not a fit

Patients with idiopathic pulmonary fibrosis, pregnant or lactating women, and those with cognitive impairments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the risk factors, prevalence, and mortality associated with progressive pulmonary fibrosis (PPF) in patients with interstitial lung disease (ILD). Participants will undergo baseline assessments, including demographic data, medical history, and various lung function tests, along with blood sampling. Follow-up visits at 6 and 12 months will repeat these assessments to track changes over time. The study focuses on patients with radiological evidence of pulmonary fibrosis, excluding those with idiopathic pulmonary fibrosis.

Why it matters

Potential benefit: If successful, this study could enhance understanding of progressive pulmonary fibrosis and inform better management strategies for patients with interstitial lung disease.

How similar studies have gone: While similar studies have explored risk factors in pulmonary fibrosis, this specific observational approach is less common and may provide novel insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18-80 years old
* Agree and sign the informed consent form
* Interstitial lung disease patients with imaging features of pulmonary fibrosis

Exclusion Criteria:

* Patients with idiopathic pulmonary fibrosis (IPF)
* Pregnant or lactating women
* mental illness or cognitive impairment
* participating in other clinical studies
* Unable to sign informed consent form

Where it's running

  • The First Affiliated Hospital of Shandong First Medical University
    Jinan, Shandong, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.