Observational study on acute intoxications in children

Multicentre Prospective Observational Study of Acute Intoxications in Paediatric Age

This study looks at how often children get sick from poisoning and what factors are involved, to help improve how we treat these cases in the future.

Quick facts

• Study type: Observational
• Enrollment: 90 (estimated)
• Ages: 1 Month to 16 Years
• Sex: All
• Sponsor: Meyer Children's Hospital IRCCS (Academic / other)
• Locations: 31 sites (Bagno a Ripoli, Firenze and 30 other locations)
• Trial ID: NCT06291649 on ClinicalTrials.gov

What this trial studies

This study aims to assess the epidemiology of acute intoxications in children, focusing on the social and care factors associated with these incidents. It is a multicentre observational cohort study conducted by AMIETOX, involving Poison Control Centres and Paediatric emergency rooms. The goal is to gather data that will inform better diagnostic and therapeutic management strategies for acute intoxications in the future.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 1 month to 16 years who experience acute intoxication.

Not a fit: Patients who do not provide informed consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved prevention and treatment strategies for acute intoxications in children.

How similar studies have performed: While similar studies have been conducted, this specific approach to understanding acute intoxications in children is relatively novel.

Eligibility criteria

Inclusion Criteria:

* Subjects between the ages of 1 month and 16 years who report to the PSPs or contact by telephone the CAVs participating in the study with acute intoxication (defined as contact with a substance that is toxic per se or in such quantities as to cause a harmful effect on the body or administered by a route not intended for that substance)

Exclusion Criteria:

* not acquired informed consent

Where this trial is running

Bagno a Ripoli, Firenze and 30 other locations

• Ospedale Santa Maria Annunziata — Bagno a Ripoli, Firenze, Italy (Recruiting)
• Ospedale Del Mugello — Borgo San Lorenzo, Firenze, Italy (Recruiting)
• Ospedale G B Morgagni — Forlì, Forlì-Cesena, Italy (Recruiting)
• Mater Salutis — Legnago, Verona, Italy (Recruiting)
• Ospedale Maggiore — Bologna, Italy (Recruiting)
• Ospedale Centrale Bolzano — Bolzano, Italy (Recruiting)
• Ospedale Brotzu — Cagliari, Italy (Recruiting)
• Ospedale San Giuseppe — Empoli, Italy (Recruiting)
• Meyer Children's Hospital IRCCS — Florence, Italy (Recruiting)
• Ospedale Misericordia — Grosseto, Italy (Recruiting)
• Policlinico Messina — Messina, Italy (Recruiting)
• Ospedale San Francesco — Nuoro, Italy (Recruiting)
• Ao Padova — Padova, Italy (Recruiting)
• Nuovo Ospedale Dei Bambini — Parma, Italy (Recruiting)
• Policlinico San Matteo — Pavia, Italy (Recruiting)
• Policlinico Pescara — Pescara, Italy (Recruiting)
• Ospedale Santa Chiara - Cisanello — Pisa, Italy (Recruiting)
• Ospedale San Jacopo — Pistoia, Italy (Recruiting)
• Ospedale Civile Santa Maria Degli Angel — Pordenone, Italy (Recruiting)
• Ospedale Santo Stefano — Prato, Italy (Recruiting)
• Ospedale Infermi — Rimini, Italy (Recruiting)
• CAV Gemelli — Roma, Italy (Recruiting)
• Policlinico Gemelli — Roma, Italy (Recruiting)
• Ospedale Regina Margherita — Torino, Italy (Recruiting)
• Santa Chiara — Trento, Italy (Recruiting)
• Ulss 2 Marca Trevigiana — Treviso, Italy (Recruiting)
• Burlo Garofalo — Trieste, Italy (Recruiting)
• Clinica Pediatrica Udine — Udine, Italy (Recruiting)
• CAV Veneto — Verona, Italy (Recruiting)
• Ospedale Della Donna E Del Bambino — Verona, Italy (Recruiting)
• Ospedale San Bortolo — Vicenza, Italy (Recruiting)

Study contacts

• Study coordinator: Marco De Luca

Conditions Acute Intoxication