Peripheral IV catheter use in children seen in the emergency room
Official title: Randomized, Open-label, Parallel-arm, Controlled Study to Evaluate the Stabilization of Peripheral Venous Catheters Through the Application of Cyanoacrylate Skin Adhesive to the Exit Site in Pediatric Patients With Emergency Room Access.
Run by Meyer Children's Hospital IRCCS · NCT07450729 · Data updated 2026-11-12
This test tries adding skin glue under the transparent dressing to help keep peripheral IVs in place for children (0–18) treated in the emergency room.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 0 Years to 18 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Meyer Children's Hospital IRCCS Academic / other |
| Locations | 1 site (Florence) |
| Status | Recruiting |
| Started | January 14, 2025 |
| Main results expected | September 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | March 5, 2026 |
| Trial ID | NCT07450729 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 0–18 who require a peripheral venous catheter expected to remain at least 24 hours, have informed guardian consent, and are not undergoing immediate surgery or coded emergencies are ideal candidates.
✕Probably not a fit
Patients with pre-existing central venous access, skin lesions at the insertion site, psychomotor agitation, emergency code status, unaccompanied minors, language barriers, or those needing immediate surgery are unlikely to be eligible or to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study at Meyer Children's Hospital compares standard transparent semipermeable dressings with dressings plus topical cyanoacrylate glue to secure peripheral venous catheters in pediatric emergency patients. Children aged 0–18 who have a peripheral venous catheter expected to remain for at least 24 hours and whose guardians provide consent will be enrolled. The study will monitor catheter stability and complications such as accidental displacement, extravasation, occlusion, phlebitis, and local infection during device dwell time. Results will show whether adding skin glue reduces device loss and related complications compared with standard dressing alone.
Why it matters
Potential benefit: If successful, adding skin glue could reduce accidental IV dislodgement and related complications, meaning fewer repeat insertions for children.
How similar studies have gone: Prior adult studies and limited pediatric reports of topical cyanoacrylate for IV securement have generally shown reduced catheter dislodgement, though pediatric evidence remains modest.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 0-18 years old * Venous access device for at least 24 hours. * Informed consent form signed Exclusion Criteria: * Patients with language barriers * patients with pre-existing central venous access * patients requiring immediate surgery with venous access placed under sedation * skin lesions in the affected area * patients exhibiting psychomotor agitation * patients assigned to the emergency code * unaccompanied minors
Where it's running
-
Meyer Children's Hospital IRCCS, Firenze
Florence, Italy Recruiting
Study contacts
- Study coordinator: Giulia Caccia, Principal Investigator
- Email: giulia.caccia@meyer.it
- Phone: 0555662629
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.