Peripheral IV catheter use in children seen in the emergency room

Randomized, Open-label, Parallel-arm, Controlled Study to Evaluate the Stabilization of Peripheral Venous Catheters Through the Application of Cyanoacrylate Skin Adhesive to the Exit Site in Pediatric Patients With Emergency Room Access.

NA · Meyer Children's Hospital IRCCS · NCT07450729

This test tries adding skin glue under the transparent dressing to help keep peripheral IVs in place for children (0–18) treated in the emergency room.

Quick facts

PhaseNA
Study typeInterventional
Enrollment300 (estimated)
Ages0 Years to 18 Years
SexAll
SponsorMeyer Children's Hospital IRCCS (other)
Locations1 site (Florence)
Trial IDNCT07450729 on ClinicalTrials.gov

What this trial studies

This interventional study at Meyer Children's Hospital compares standard transparent semipermeable dressings with dressings plus topical cyanoacrylate glue to secure peripheral venous catheters in pediatric emergency patients. Children aged 0–18 who have a peripheral venous catheter expected to remain for at least 24 hours and whose guardians provide consent will be enrolled. The study will monitor catheter stability and complications such as accidental displacement, extravasation, occlusion, phlebitis, and local infection during device dwell time. Results will show whether adding skin glue reduces device loss and related complications compared with standard dressing alone.

Who should consider this trial

Good fit: Children aged 0–18 who require a peripheral venous catheter expected to remain at least 24 hours, have informed guardian consent, and are not undergoing immediate surgery or coded emergencies are ideal candidates.

Not a fit: Patients with pre-existing central venous access, skin lesions at the insertion site, psychomotor agitation, emergency code status, unaccompanied minors, language barriers, or those needing immediate surgery are unlikely to be eligible or to benefit.

Why it matters

Potential benefit: If successful, adding skin glue could reduce accidental IV dislodgement and related complications, meaning fewer repeat insertions for children.

How similar studies have performed: Prior adult studies and limited pediatric reports of topical cyanoacrylate for IV securement have generally shown reduced catheter dislodgement, though pediatric evidence remains modest.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 0-18 years old
* Venous access device for at least 24 hours.
* Informed consent form signed

Exclusion Criteria:

* Patients with language barriers
* patients with pre-existing central venous access
* patients requiring immediate surgery with venous access placed under sedation
* skin lesions in the affected area
* patients exhibiting psychomotor agitation
* patients assigned to the emergency code
* unaccompanied minors

Where this trial is running

Florence

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Venous Catheterization

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.