Observational study of dementia in elderly Chinese patients
Official title: Peking Union Medical College Hospital (PUMCH) Dementia Longitudinal Cohort Study
Run by Peking Union Medical College Hospital · NCT05023564 · Data updated 2026-11-12
This study looks at older Chinese adults with dementia to see how lifestyle and stress affect their condition and to track their cognitive health over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 20000 (estimated) |
| Sponsor | Peking Union Medical College Hospital Academic / other |
| Locations | 1 site (Beijing) |
| Status | Recruiting |
| Started | December 1, 2020 |
| Main results expected | December 31, 2040 |
| Study ends | December 31, 2040 |
| Registry record updated | September 13, 2022 |
| Trial ID | NCT05023564 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are elderly individuals diagnosed with neurodegenerative dementia who have a fixed caregiver and can participate in regular follow-ups.
✕Probably not a fit
Patients who are not diagnosed with dementia, including those with mild cognitive impairment, or those with severe systemic diseases affecting follow-up will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The PUMCH Dementia Longitudinal Cohort Study is an observational study focused on elderly individuals in China diagnosed with various forms of dementia. It aims to establish a comprehensive database by collecting detailed clinical information, conducting neuropsychological evaluations, and storing biological samples. The study will explore the relationships between lifestyle factors, stress, and dementia, assess risk factors, and evaluate behavioral and psychological symptoms associated with the condition. Patients will be followed up every six months to monitor their cognitive health and gather longitudinal data.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis, treatment strategies, and preventive measures for dementia in the elderly population.
How similar studies have gone: Other studies focusing on dementia in elderly populations have shown success in identifying risk factors and improving care, making this approach both relevant and potentially impactful.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Neurodegenerative dementia diagnosis based on 2011 NIA-AA criteria of Dementia * Fixed care giver and can follow up regularly Exclusion Criteria: * Not demented, including MCI * Systemic severe diseases and severe vision or hearing problem effecting follow up and neuropsychological evaluation * Without fixed care giver * Reject informed consent * Expected life shorter than 2 years
Where it's running
-
Peking Union Medical College Hospital
Beijing, China Recruiting
Study contacts
- Principal investigator: Chenhui Mao, Doctor — Peking Union Medical College Hospital
- Study coordinator: Chenhui Mao, Doctor
- Email: maochenhui@pumch.cn
- Phone: +86018611895308
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.